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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
C-X-C motif chemokine receptor 4 S homeolog
Summary
- Gene Symbol
-
- cxcr4.S
- Organism
- Xenopus laevis (African clawed frog)
Annotation
- Keyword
-
- Cell membrane
- Cytoplasm
- Disulfide bond
- Endosome
- G-protein coupled receptor
- Gastrulation
- Glycoprotein
- Lysosome
- Nucleus
- Reference proteome
- Sulfation
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A974BUH0 |
|
| Q7ZXJ7 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| immune response | ||
| neurogenesis | ||
| positive regulation of cytosolic calcium ion concentration | ||
| G protein-coupled receptor signaling pathway |
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| membrane | ||
| early endosome | ||
| late endosome | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| chemokine receptor activity | ||
| C-X-C chemokine receptor activity | ||
| C-C chemokine receptor activity | ||
| G protein-coupled receptor activity | ||
| C-C chemokine binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| C-C chemokine binding |
| C-C chemokine receptor activity |
| brain development |
| calcium-mediated signaling |
| cell chemotaxis |
| chemokine receptor activity |
| chemokine-mediated signaling pathway |
| chemotaxis |
| immune response |
| neurogenesis |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2600 | laryngeal carcinoma | |
| DOID:3347 | osteosarcoma | |
| DOID:3748 | esophagus squamous cell carcinoma | |
| DOID:3753 | Hermansky-Pudlak syndrome | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:3910 | lung adenocarcinoma | |
| DOID:4074 | pancreatic adenocarcinoma | |
| DOID:4467 | clear cell renal cell carcinoma | |
| DOID:4531 | mucoepidermoid carcinoma | |
| DOID:5241 | hemangioblastoma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 119544938 | 27675_0:002d24 | |||
| 119827638 | 1047088_0:004453 | |||
| 119932284 | 9261_0:00159f | |||
| 120508805 | 9160_0:000052 | |||
| 120944142 | 8407_0:00360c | |||
| 121008243 | 8384_0:004113 | |||
| 121931002 | 8520_0:0009ef | |||
| 122749007 | 33562_0:00331f | |||
| 122944750 | 30331_0:004204 | |||
| 123027385 | 61221_0:00249d |
