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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
C-X-C motif chemokine receptor 4 S homeolog
Summary
- Gene Symbol
-
- cxcr4.S
- Organism
- Xenopus laevis (African clawed frog)
Annotation
- Keyword
-
- Cell membrane
- Cytoplasm
- Disulfide bond
- Endosome
- G-protein coupled receptor
- Gastrulation
- Glycoprotein
- Lysosome
- Nucleus
- Reference proteome
- Sulfation
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A974BUH0 |
|
| Q7ZXJ7 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| chemotaxis | ||
| germ cell migration | ||
| brain development | ||
| calcium-mediated signaling | ||
| cell chemotaxis |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| chemokine receptor activity | ||
| C-X-C chemokine receptor activity | ||
| C-C chemokine receptor activity | ||
| G protein-coupled receptor activity | ||
| C-C chemokine binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| positive regulation of cytosolic calcium ion concentration |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050909 | extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue | |
| DOID:0060284 | paroxysmal nocturnal hemoglobinuria | |
| DOID:0060591 | WHIM syndrome | |
| DOID:0060901 | lymphoplasmacytic lymphoma | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:10283 | prostate cancer | |
| DOID:10534 | stomach cancer | |
| DOID:11476 | osteoporosis | |
| DOID:1993 | rectum cancer | |
| DOID:2596 | larynx cancer |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 128341052 | 884348_0:0005cc | |||
| 128501389 | 233779_0:003168 | |||
| 128645333 | 8345_0:000708 | |||
| 128912245 | 75485_0:001f94 | |||
| 129061872 | 1884717_0:00460c | |||
| 129200405 | 9117_0:0041ee | |||
| 129208312 | 9117_0:0019a4 | |||
| 129323432 | 481883_0:000d88 | |||
| 130284403 | 327740_0:003e9b | |||
| 130487796 | 460621_0:00388c |
