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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
C-X-C motif chemokine receptor 4 S homeolog
Summary
- Gene Symbol
-
- cxcr4.S
- Organism
- Xenopus laevis (African clawed frog)
Annotation
- Keyword
-
- Cell membrane
- Cytoplasm
- Disulfide bond
- Endosome
- G-protein coupled receptor
- Gastrulation
- Glycoprotein
- Lysosome
- Nucleus
- Reference proteome
- Sulfation
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A974BUH0 |
|
| Q7ZXJ7 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| chemotaxis | ||
| germ cell migration | ||
| brain development | ||
| calcium-mediated signaling | ||
| cell chemotaxis |
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| membrane | ||
| early endosome | ||
| late endosome | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| chemokine receptor activity | ||
| C-X-C chemokine receptor activity | ||
| C-C chemokine receptor activity | ||
| G protein-coupled receptor activity | ||
| C-C chemokine binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| C-C chemokine binding |
| C-C chemokine receptor activity |
| brain development |
| calcium-mediated signaling |
| cell chemotaxis |
| chemokine receptor activity |
| chemokine-mediated signaling pathway |
| chemotaxis |
| immune response |
| neurogenesis |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050909 | extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue | |
| DOID:0060284 | paroxysmal nocturnal hemoglobinuria | |
| DOID:0060591 | WHIM syndrome | |
| DOID:0060901 | lymphoplasmacytic lymphoma | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:10283 | prostate cancer | |
| DOID:10534 | stomach cancer | |
| DOID:11476 | osteoporosis | |
| DOID:1993 | rectum cancer | |
| DOID:2596 | larynx cancer |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 130858707 | 575201_0:002df5 | |||
| 131203520 | 499056_0:0008de | |||
| 131410690 | 77932_0:00197a | |||
| 131925198 | 42410_0:0040b9 |
