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MIRAGE
kallikrein 1
Summary
- Gene Symbol
-
- KLK1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Reference proteome
- Serine protease
- Signal
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A1R3UCD2 |
|
| P06870 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of systemic arterial blood pressure | ||
| zymogen activation |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space | ||
| nucleus | ||
| secretory granule | ||
| extracellular exosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| serine-type endopeptidase activity | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- serine protease
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| proteolysis |
| serine-type endopeptidase activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050700 | cardiomyopathy | |
| DOID:10763 | hypertension | |
| DOID:5844 | myocardial infarction | |
| DOID:783 | end stage renal disease | |
| DOID:784 | chronic kidney disease |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 354 | FB:FBgn0052808 | ||
| 3816 | FB:FBgn0052808 | ||
| 3817 | FB:FBgn0052808 | ||
| 5650 | RGD:1306420 | ||
| 5653 | FB:FBgn0052808 | ||
| 5655 | RGD:1303242 | ||
| 11012 | FB:FBgn0052808 | ||
| 11202 | FB:FBgn0052808 | ||
| 13646 | FB:FBgn0052808 | MOUSE51803 | |
| 13647 | FB:FBgn0052808 | MOUSE51793 |
