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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
kallikrein 1
Summary
- Gene Symbol
-
- KLK1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Reference proteome
- Serine protease
- Signal
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A1R3UCD2 |
|
| P06870 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of systemic arterial blood pressure | ||
| zymogen activation |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| secretory granule | ||
| extracellular space | ||
| nucleus | ||
| extracellular exosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- chymotrypsin
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050700 | cardiomyopathy | |
| DOID:10763 | hypertension | |
| DOID:4989 | pancreatitis | |
| DOID:5844 | myocardial infarction | |
| DOID:783 | end stage renal disease | |
| DOID:784 | chronic kidney disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 13646 | MGI:95291 | MOUSE51803 | ||
| 13647 | MGI:95292 | MOUSE51793 | ||
| 13648 | MGI:95293 | MOUSE51786 | ||
| 16612 | MGI:102850 | MOUSE51828 | ||
| 16613 | MGI:892023 | MOUSE51790 | ||
| 16615 | MGI:891982 | MOUSE51814 | ||
| 16616 | MGI:892022 | MOUSE51802 | ||
| 16617 | MGI:892021 | MOUSE51816 | ||
| 16618 | MGI:891981 | MOUSE51793 | ||
| 16619 | MGI:891980 | MOUSE51796 |
