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MIRAGE
Kallikrein-1

Summary
UniProt ID
P06870
Gene Symbol
  • KLK1
Gene ID
3816
Organism
Homo sapiens (human)
GlyConnect
GlyGen
P06870
PubChem
P06870
The Human Metabolome Database
HMDBP13675
Re-Glyco
P06870
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Reference proteome
  • Serine protease
  • Signal
  • Zymogen
Gene Ontology (GO)
Displaying all 4 entries
GO Term
extracellular exosome
extracellular space
nucleus
secretory granule
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying 1 entry
GO Term
serine-type endopeptidase activity
Annotation information from UniProt.
Sequence
MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIAENS
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 7 entries
Position Description PubMed ID GlyTouCan ID Source
93 O-linked (GalNAc...) serine
102 N-linked (GlcNAc...) asparagine
104 O-linked (GalNAc...) serine
108 N-linked (GlcNAc...) asparagine
165 N-linked (GlcNAc...) asparagine; partial
167 O-linked (GalNAc...) serine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Regulation of IGF Activity by IGFBP Homo sapiens
Disease
Displaying all 5 entries
DO ID Disease Name Source
DOID:0050700 cardiomyopathy
DOID:10763 hypertension
DOID:5844 myocardial infarction
DOID:783 end stage renal disease
DOID:784 chronic kidney disease
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025