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MIRAGE
hypocretin (orexin) receptor 2
Summary
- Gene Symbol
-
- Hcrtr2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P58308 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled receptor signaling pathway | ||
| phospholipase C-activating G protein-coupled receptor signaling pathway | ||
| neuropeptide signaling pathway | ||
| neuropeptide signaling pathway | ||
| neuropeptide signaling pathway |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleoplasm | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled receptor activity | ||
| protein binding | ||
| orexin receptor activity | ||
| orexin receptor activity | ||
| orexin receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- orexin receptor type 2
- Functional Category
-
- I: Lipid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| circadian sleep/wake cycle process |
| orexin receptor activity |
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
| Orexin receptor 2 |
| Orexin receptor family |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:8986 | narcolepsy |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 103268734 | CARSF25321 | ||
| 103663986 | URSMA13746 | ||
| 103744374 | NANGA18968 | ||
| 103819937 | SERCA02750 | ||
| 104671619 | RHIRO34330 | ||
| 105302078 | PTEVA12416 | ||
| 105479550 | MACNE17126 | ||
| 105540586 | MANLE14238 | ||
| 105590090 | CERAT04443 | ||
| 105709647 | AOTNA15014 |
