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MIRAGE
ras homolog family member A
Summary
- Gene Symbol
-
- RHOA
- Aliases
-
- RHOH12
- Rho12
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ADP-ribosylation
- Cell division
- Cell membrane
- Cell projection
- Cytoskeleton
- Direct protein sequencing
- Disease variant
- Ectodermal dysplasia
- GTP-binding
- Glycoprotein
- Host-virus interaction
- Hydrolase
- Isopeptide bond
- Lipoprotein
- Magnesium
- Membrane
- Methylation
- Nucleus
- Phosphoprotein
- Prenylation
- Proteomics identification
- Proto-oncogene
- Reference proteome
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P61586 |
|
| B4DKN9 |
|
| A0A024R324 |
|
| C9JX21 |
|
| C9JRM1 |
|
| A0A7I2YQV1 |
|
| Q9BVT0 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell morphogenesis | ||
| neuron migration | ||
| kidney development | ||
| angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure | ||
| alpha-beta T cell lineage commitment |
GO Hierarchy
biological process
cellular process [inference]
multicellular organismal process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of cellular component biogenesis [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of cellular component organization [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
regulation of epithelial cell migration [inference]
regulation of system process [inference]
regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| GTPase activity | ||
| GTPase activity | ||
| GTPase activity | ||
| GTPase activity | ||
| G protein activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- GTPase
- Functional Category
-
- T: Signal transduction mechanisms
- U: Intracellular trafficking, secretion, and vesicular transport
| Gene Ontology |
|---|
| GTP binding |
| nucleotide binding |
| protein kinase binding |
| small GTPase-mediated signal transduction |
| InterPro |
|---|
| P-loop containing nucleoside triphosphate hydrolase |
| Small GTP-binding protein domain |
| Small GTPase Rho |
| Small GTPase |
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3459 | breast carcinoma |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0003577 | Congenital onset |
| HP:0004552 | Scarring alopecia of scalp |
| HP:0006297 | Enamel hypoplasia |
| HP:0006335 | Persistence of primary teeth |
| HP:0007663 | Reduced visual acuity |
| HP:0007946 | Unilateral narrow palpebral fissure |
| HP:0009779 | 3-4 toe syndactyly |
| HP:0009918 | Ectopia pupillae |
| HP:0009928 | Thick nasal alae |
| HP:0010055 | Broad hallux |
| Disease ID | Disease Name |
|---|---|
| OMIM:618727 |
|
PubChem Disease
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 387 | Xenbase:XB-GENE-941426 | ||
| 388 | SGD:S000006369 | ||
| 389 | Xenbase:XB-GENE-941426 | ||
| 406411 | Xenbase:XB-GENE-941426 | ||
| 406659 | Xenbase:XB-GENE-941426 | ||
| 436718 | Xenbase:XB-GENE-941426 | ||
| 461014 | PANTR31134 | ||
| 856294 | Xenbase:XB-GENE-941426 | ||
| 100006041 | Xenbase:XB-GENE-489222 | ||
| 100171605 | PONAB25992 |
