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ras homolog gene family, member Aa

Summary

Gene Symbol

rhoaa

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

406411

PubChem

406411

Alliance of Genome Resources

ZFIN:ZDB-GENE-040426-2150

Annotation

Keyword

Cell membrane
GTP-binding
Glycoprotein
Methylation
Prenylation
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6NUX8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
skeletal muscle satellite cell migration	ISS
wound healing, spreading of cells	ISS
small GTPase mediated signal transduction	IEA
actin filament organization	IBA
signal transduction	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction

intracellular signal transduction [inference]

small GTPase mediated signal transduction

cell motility [inference]

cell migration [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

supramolecular fiber organization [inference]

actin filament organization

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

intracellular signal transduction [inference]

small GTPase mediated signal transduction

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IEA
plasma membrane	IBA IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
GTPase activity	IBA IEA
nucleotide binding	IEA
GTP binding	IBA IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cell division control protein 42

Functional Category

K: Transcription
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
GTP binding
nucleotide binding
protein kinase binding
small GTPase-mediated signal transduction

Displaying **all 4** entries
InterPro
P-loop containing nucleoside triphosphate hydrolase
Small GTP-binding protein domain
Small GTPase Rho
Small GTPase

Disease

Disease Ontology

Displaying entries **1 - 10** of 16 in total

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DO ID	Disease Name	Source
DOID:0050665	fetal alcohol syndrome	Alliance of Genome Resources
DOID:0080377	peroxisomal biogenesis disorder	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:10976	membranous glomerulonephritis	Alliance of Genome Resources
DOID:11054	urinary bladder cancer	Alliance of Genome Resources
DOID:1289	neurodegenerative disease	Alliance of Genome Resources
DOID:1612	breast cancer	Alliance of Genome Resources
DOID:2377	multiple sclerosis	Alliance of Genome Resources
DOID:2841	asthma	Alliance of Genome Resources
DOID:3459	breast carcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **592** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	387		HGNC:667
Mus musculus	11848		MGI:1096342
Drosophila melanogaster	36775		FB:FBgn0014020
Rattus norvegicus	117273		RGD:619921
Caenorhabditis elegans	178458		WB:WBGene00004357
Xenopus tropicalis	549323		Xenbase:XB-GENE-941426
Saccharomyces cerevisiae S288C	855634		SGD:S000005034
Saccharomyces cerevisiae S288C	856294		SGD:S000006369
Ictalurus punctatus	100528424	7998_0:0010dc		ICTPU30033
Oreochromis niloticus	100693083	8128_0:0058a5

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements