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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
lactate dehydrogenase A
Summary
- Gene Symbol
-
- LDHA
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Glycogen storage disease
- Isopeptide bond
- NAD
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| substantia nigra development |
|
|
| pyruvate metabolic process | ||
| glycolytic process | ||
| lactate metabolic process |
GO Hierarchy
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
catabolic process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
aromatic compound catabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
cellular catabolic process [inference]
heterocycle metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
heterocycle catabolic process [inference]
primary metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
organophosphate metabolic process [inference]
organic cyclic compound metabolic process [inference]
organonitrogen compound metabolic process [inference]
organic substance catabolic process [inference]
cellular process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
aromatic compound catabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
cellular catabolic process [inference]
heterocycle metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
heterocycle catabolic process [inference]
GO Hierarchy
GO Hierarchy
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0014667 | disease of metabolism | |
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:0050387 | nonpapillary renal cell carcinoma | |
| DOID:0050646 | distal arthrogryposis | |
| DOID:0050700 | cardiomyopathy | |
| DOID:0050902 | medulloblastoma | |
| DOID:0060058 | lymphoma | |
| DOID:0060161 | Kennedy's disease | |
| DOID:0070322 | childhood hepatocellular carcinoma | |
| DOID:0070328 | adult hepatocellular carcinoma |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000083 | Renal insufficiency |
| HP:0000989 | Pruritus |
| HP:0001036 | Parakeratosis |
| HP:0001787 | Abnormal delivery |
| HP:0001919 | Acute kidney injury |
| HP:0002046 | Heat intolerance |
| HP:0002063 | Rigidity |
| HP:0002151 | Increased circulating lactate concentration |
| HP:0002910 | Elevated circulating hepatic transaminase concentration |
| Disease ID | Disease Name |
|---|---|
| ORPHA:284426 |
|
| OMIM:612933 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 174798 | WB:WBGene00002262 | ||
| 45880 | FB:FBgn0001258 | ||
| 100174998 | CIOIN04295 | ||
| 30496 | ZFIN:ZDB-GENE-991026-5 | DANRE26864 | |
| 103047177 | ASTMX00339 | ||
| 100529018 | ICTPU06635 | ||
| 113581310 | ELEEL27581 | ||
| 100194556 | SALSA80180 | ||
| 106573043 | SALSA80180 | ||
| 115152410 | SALTR115653 |
