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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
L-lactate dehydrogenase A chain
Summary
- UniProt ID
- P00338
- Gene Symbol
-
- LDHA
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Glycogen storage disease
- Isopeptide bond
- NAD
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| substantia nigra development |
| pyruvate metabolic process |
| glycolytic process |
| lactate metabolic process |
| GO Term |
|---|
| nucleus |
| membrane |
| extracellular exosome |
| mitochondrion |
| cytosol |
| oxidoreductase complex |
| GO Term |
|---|
| cadherin binding |
| identical protein binding |
| L-lactate dehydrogenase activity |
Sequence
MATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF
Glycosylation Sites
G49108TO
G57776ZS
G43223CG
G92406TI
G41247ZX
G84225JN
G70994MS
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Pyruvate metabolism | Homo sapiens |
| Regulation of pyruvate metabolism | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070328 | adult hepatocellular carcinoma | |
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:0050387 | nonpapillary renal cell carcinoma | |
| DOID:0050646 | distal arthrogryposis | |
| DOID:0050700 | cardiomyopathy | |
| DOID:0050902 | medulloblastoma | |
| DOID:0060058 | lymphoma | |
| DOID:0060161 | Kennedy's disease | |
| DOID:0070322 | childhood hepatocellular carcinoma | |
| DOID:0080108 | myoglobinuria |
