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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
leptin
Summary
- Gene Symbol
-
- LEP
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of cytokine production involved in inflammatory response | ||
| response to insulin | ||
| bone mineralization involved in bone maturation | ||
| cholesterol metabolic process | ||
| regulation of intestinal cholesterol absorption |
GO Hierarchy
- positive regulation of cold-induced thermogenesis
- positive regulation of cold-induced thermogenesis
- regulation of cell cycle
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
positive regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell population proliferation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of cellular localization [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
regulation of system process [inference]
regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytosol | ||
| extracellular region | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA binding | ||
| hormone activity | ||
| peptide hormone receptor binding | ||
| protein binding | ||
| leptin receptor binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11394 | adult respiratory distress syndrome | |
| DOID:11476 | osteoporosis | |
| DOID:1168 | familial hyperlipidemia | |
| DOID:11714 | gestational diabetes | |
| DOID:12236 | primary biliary cholangitis | |
| DOID:12858 | Huntington's disease | |
| DOID:14018 | alcoholic liver cirrhosis | |
| DOID:14221 | abdominal obesity-metabolic syndrome 1 | |
| DOID:14330 | Parkinson's disease | |
| DOID:1485 | cystic fibrosis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 105598538 | CERAT05219 | ||
| 102136844 | MACFA30282 | ||
| 698728 | MACMU33263 | ||
| 105474689 | MACNE22316 | ||
| 101014968 | PAPAN30678 | ||
| 105550852 | MANLE00919 | ||
| 101130896 | GORGO38509 | ||
| 100983807 | PANPA37122 | ||
| 449638 | PANTR41327 | ||
| 100440463 | PONAB32759 |
