lipase C, hepatic type

Summary
Gene Symbol
  • LIPC
Aliases
  • HL
  • HTGL
  • Triacylglycerol lipase
Organism
Homo sapiens (human)
External Links
NCBI Gene
3990
HGNC
6619
KEGG Gene ID
hsa:3990
PubChem
3990
Alliance of Genome Resources
Annotation
Keyword
  • Calcium
  • Direct protein sequencing
  • Disease variant
  • Glycoprotein
  • HDL
  • Heparin-binding
  • Hydrolase
  • Lipid degradation
  • Metal-binding
  • Reference proteome
  • Secreted
  • Signal
Proteins
Displaying all 2 entries
UniProt Protein Name
A6H8L5
  • Lipase member C
  • Lysophospholipase
  • Phospholipase A1
P11150
  • Lipase member C
  • Lysophospholipase
  • Phospholipase A1
Gene Ontology (GO)
GO Hierarchy
KEGG BRITE Database
Orthology
K22283
Name
hepatic triacylglycerol lipase [EC:3.1.1.3]
References
Disease
Disease Ontology
Displaying entries 1 - 10 of 125 in total
DO ID Disease Name Source
DOID:0040085 bacterial sepsis
DOID:0050328 congenital hypothyroidism
DOID:0050747 obsolete lymphoplasmacytic lymphoma
DOID:0050782 Zollinger-Ellison syndrome
DOID:0050830 peripheral artery disease
DOID:0060224 atrial fibrillation
DOID:0060250 idiopathic scoliosis
DOID:0080199 colorectal carcinoma
DOID:0080348 Alzheimer's disease 1
DOID:0110035 Alzheimer's disease 2
The Human Phenotype Ontology
Displaying entries 1 - 10 of 12 in total
HPO ID HPO Term
HP:0000006 Autosomal dominant inheritance
HP:0000007 Autosomal recessive inheritance
HP:0000855 Insulin resistance
HP:0001013 Eruptive xanthomas
HP:0001084 Corneal arcus
HP:0001681 Angina pectoris
HP:0002155 Hypertriglyceridemia
HP:0003124 Hypercholesterolemia
HP:0003584 Late onset
HP:0005181 Premature coronary artery atherosclerosis
Displaying all 3 entries
Disease ID Disease Name
OMIM:614025
  • hyperlipidemia due to hepatic triglyceride lipase deficiency
ORPHA:140905
  • hyperlipidemia due to hepatic triglyceride lipase deficiency
OMIM:125853
  • type 2 diabetes mellitus
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP001696
Gene Name
lipase, hepatic

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024