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Hepatic triacylglycerol lipase

Summary

UniProt ID

P11150

Gene Symbol

LIPC
HTGL

Organism

Homo sapiens (human)

External Links

GlyGen

P11150

PubChem

P11150

SwissLipids

SLP:000000569

The Human Metabolome Database

HMDBP00226

Annotation

Keyword

Direct protein sequencing
Disease variant
Glycoprotein
HDL
Heparin-binding
Hydrolase
Lipid degradation
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 12 in total

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GO Term
phosphatidylcholine catabolic process
intermediate-density lipoprotein particle remodeling
fatty acid biosynthetic process
cholesterol metabolic process
triglyceride catabolic process
very-low-density lipoprotein particle remodeling
low-density lipoprotein particle remodeling
high-density lipoprotein particle remodeling
chylomicron remnant clearance
cholesterol homeostasis

Displaying **all 4** entries
GO Term
endoplasmic reticulum lumen
extracellular region
extracellular space
high-density lipoprotein particle

Displaying **all 10** entries
GO Term
heparin binding
phosphatidylserine 1-acylhydrolase activity
1-acyl-2-lysophosphatidylserine acylhydrolase activity
lipoprotein lipase activity
phospholipase activity
triglyceride lipase activity
low-density lipoprotein particle binding
apolipoprotein binding
lysophospholipase activity
phospholipase A1 activity

Annotation information from UniProt.

Sequence

MDTSPLCFSILLVLCIFIQSSALGQSLKPEPFGRRAQAVETNKTLHEMKTRFLLFGETNQGCQIRINHPDTLQECGFNSSLPLVMIIHGWSVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRNTRLVGKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLFEGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPIGHYDFYPNGGSFQPGCHFLELYRHIAQHGFNAITQTIKCSHERSVHLFIDSLLHAGTQSMAYPCGDMNSFSQGLCLSCKKGRCNTLGYHVRQEPRSKSKRLFLVTRAQSPFKVYHYQFKIQFINQTETPIQTTFTMSLLGTKEKMQKIPITLGKGIASNKTYSFLITLDVDIGELIMIKFKWENSAVWANVWDTVQTIIPWSTGPRHSGLVLKTIRVKAGETQQRMTFCSENTDDLLLRPTQEKIFVKCEIKSKTSKRKIR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	GlyTouCan ID	Source
42	N-linked (GlcNAc...) asparagine	G68490OW G27947YN G85282JO G45395BF G07246CJ G14972EH G00912UN G92551JA G87661QW G17208MA G46691LC G04657PL G83460ZZ G10488MI G41071NU G07755XJ G80920RR G62765YT G31852PQ	UniProt GlyGen
78	N-linked (GlcNAc...) asparagine		UniProt GlyGen
362	N-linked (GlcNAc...) asparagine	G00273SJ G08918WF G00912UN G87661QW G83646BJ G43769HG G41071NU G86182NS G42124LM G90659AW G45504EY G62765YT	UniProt GlyGen
397	N-linked (GlcNAc...) asparagine		UniProt GlyGen