matrix metallopeptidase 12

Summary
Gene Symbol
  • MMP12
Organism
Homo sapiens (human)
NCBI Gene
4321
PubChem
4321
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Calcium
  • Disulfide bond
  • Extracellular matrix
  • Glycoprotein
  • Metal-binding
  • Metalloprotease
  • Reference proteome
  • Repeat
  • Signal
  • Zinc
  • Zymogen
Proteins
Displaying 1 entry
UniProt Protein Name
P39900
  • Macrophage elastase
  • Matrix metalloproteinase-12
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
metallopeptidase
Functional Category
  • M: Cell wall/membrane/envelope biogenesis
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying all 7 entries
DO ID Disease Name Source
DOID:2349 arteriosclerosis
DOID:2377 multiple sclerosis
DOID:3362 coronary aneurysm
DOID:3393 coronary artery disease
DOID:4914 esophagus adenocarcinoma
DOID:7693 abdominal aortic aneurysm
DOID:9206 Barrett's esophagus
Ortholog
Displaying entries 71 - 74 of 74 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
110214965 PHACI18009
112925878 VULVU20045
113905149 BOBOX35137
117030621 RHIFE29268

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025