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BPI fold containing family A member 1

Summary

Gene Symbol

BPIFA1

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 449524
PubChem: 449524

Annotation

Keyword

Antibiotic
Disulfide bond
Glycoprotein
Innate immunity
Lipid-binding
Reference proteome
Secreted
Signal

Proteins

Displaying **all 3** entries
UniProt	Protein Name
K7GS01	Palate lung and nasal epithelium clone protein
Q5XW65	Lung and nasal epithelium carcinoma-associated protein Palate lung and nasal epithelium clone protein
A0A8D1D3G3	Palate lung and nasal epithelium clone protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
multicellular organismal-level water homeostasis
antibacterial humoral response	IEA	30032202
negative regulation of single-species biofilm formation in or on host organism	IEA	30032202
immune response in nasopharyngeal-associated lymphoid tissue	IEA	30032202
innate immune response	IEA	30032202

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

immune response in gut-associated lymphoid tissue [inference]

immune response in nasopharyngeal-associated lymphoid tissue

humoral immune response [inference]

antimicrobial humoral response [inference]

innate immune response

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

chemical homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

antibacterial humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

antibacterial humoral response

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

antibacterial humoral response

innate immune response

immune response [inference]

immune response in gut-associated lymphoid tissue [inference]

immune response in nasopharyngeal-associated lymphoid tissue

humoral immune response [inference]

antimicrobial humoral response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

antibacterial humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

antibacterial humoral response

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

antibacterial humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

antibacterial humoral response

innate immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

regulation of sodium ion transmembrane transport

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport

regulation of biological process involved in symbiotic interaction [inference]

regulation of single-species biofilm formation in or on host organism [inference]

negative regulation of single-species biofilm formation in or on host organism

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport

negative regulation of cellular process [inference]

negative regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of single-species biofilm formation in or on host organism [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of biological quality [inference]

regulation of body fluid levels [inference]

multicellular organismal-level water homeostasis

Displaying 1 entry
GO Term	Evidence Code	PMID
extracellular space	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

Displaying 1 entry
GO Term	Evidence Code	PMID
lipid binding	IEA	22301074

GO Hierarchy

molecular function

binding [inference]

lipid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

BPI fold-containing family A member 1

Functional Category

I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
antimicrobial humoral immune response mediated by antimicrobial peptide
immune response in nasopharyngeal-associated lymphoid tissue
lipid binding
negative regulation of single-species biofilm formation in or on host organism

Displaying **all 2** entries
InterPro
Bactericidal permeability-increasing protein, alpha/beta domain superfamily
Lipid-binding serum glycoprotein, N-terminal

Ortholog

Displaying entries **1 - 10** of 63 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Mus musculus	18843		MOUSE32047
Homo sapiens	51297		HUMAN56535
Rattus norvegicus	246238		RATNO26092
Bos taurus	281989	9913_0:002680	BOVIN05101
Pan troglodytes	458177		PANTR24643
Canis lupus familiaris	609982		CANLF09451
Macaca mulatta	714509		MACMU02894
Monodelphis domestica	100032873		MONDO08858
Callithrix jacchus	100406570		CALJA35320
Pongo abelii	100462084		PONAB20296