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interleukin 1 receptor accessory protein like 1

Summary

Gene Symbol

IL1RAPL1

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 450116
PubChem: 450116

Annotation

Keyword

Cell membrane
Cell projection
Cytoplasm
Disulfide bond
Glycoprotein
Hydrolase
Immunoglobulin domain
NAD
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P60029	Oligophrenin-4 X-linked interleukin-1 receptor accessory protein-like 1
A0A2J8L3A8	X-linked interleukin-1 receptor accessory protein-like 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
trans-synaptic signaling by trans-synaptic complex
regulation of neuron projection development
regulation of presynapse assembly
negative regulation of exocytosis	IEA	30032202
regulation of postsynapse organization

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

trans-synaptic signaling by trans-synaptic complex

signal transduction

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

trans-synaptic signaling by trans-synaptic complex

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of exocytosis

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

negative regulation of exocytosis

negative regulation of secretion by cell [inference]

negative regulation of exocytosis

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of exocytosis

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

negative regulation of exocytosis

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of secretion by cell [inference]

negative regulation of exocytosis

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of exocytosis

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of cellular process [inference]

signal transduction

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

negative regulation of cellular process [inference]

negative regulation of secretion by cell [inference]

negative regulation of exocytosis

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of presynapse organization [inference]

regulation of presynapse assembly

regulation of postsynapse organization

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

negative regulation of exocytosis

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

negative regulation of exocytosis

negative regulation of secretion by cell [inference]

negative regulation of exocytosis

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane
dendrite
axon
cytoplasm
glutamatergic synapse

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
NAD+ nucleosidase activity
NAD+ nucleotidase, cyclic ADP-ribose generating

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

NAD+ nucleosidase activity

NAD+ nucleotidase, cyclic ADP-ribose generating

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Hominidae

Group Name

interleukin-1 receptor accessory protein-like 1

Functional Category

K: Transcription
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
hydrolase activity
negative regulation of exocytosis
regulation of postsynapse organization
regulation of presynapse assembly
trans-synaptic signaling by trans-synaptic complex

Displaying **all 10** entries
InterPro
IL-1Ra-like, immunoglobulin domain
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Immunoglobulin
Interleukin-1 receptor family
Toll/interleukin-1 receptor homology (TIR) domain superfamily
Toll/interleukin-1 receptor homology (TIR) domain

Rhea

RHEA:16301

H₂O + NAD⁺

H⁺ + nicotinamide + ADP-D-ribose

Enzyme

PMID

Ortholog

Displaying entries **1 - 10** of 51 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	11141	9606_0:004897	HUMAN100092
Rattus norvegicus	317553		RATNO44330
Mus musculus	331461		MOUSE66201
Macaca mulatta	706588		MACMU47297
Equus caballus	100052404		HORSE44523
Ornithorhynchus anatinus	100074745		ORNAN06918
Callithrix jacchus	100399196		CALJA47140
Pongo abelii	100443499	9601_0:005215	PONAB37663
Nomascus leucogenys	100604188		NOMLE38290
Oreochromis niloticus	100693228		ORENI45011