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Standards Ontologies Notations
fucosyltransferase 1

Summary
Gene Symbol
  • FUT1
Organism
Pan troglodytes (chimpanzee)
NCBI Gene
468947
KEGG Gene ID
ptr:468947
PubChem
468947
Annotation
Keyword
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Lipid metabolism
  • Reference proteome
  • Signal-anchor
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
Q9TUD6
  • Alpha(1,2)FT 1
  • Fucosyltransferase 1
  • GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1
  • Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT1
  • Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT1
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 11 in total
GO Term Evidence Code PMID
regulation of cell adhesion
olfactory bulb development
positive regulation of endothelial cell-matrix adhesion via fibronectin
fucosylation
positive regulation of sprouting angiogenesis
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Hominidae
Group Name
galactoside alpha-(1,2)-fucosyltransferase 1
Functional Category
  • C: Energy production and conversion
  • P: Inorganic ion transport and metabolism
  • Q: Secondary metabolites biosynthesis, transport and catabolism
  • V: Defense mechanisms
Displaying 1 entry
Gene Ontology
galactoside 2-alpha-L-fucosyltransferase activity
KEGG BRITE Database
Orthology
K00718
Name
galactoside 2-L-fucosyltransferase 1/2 [EC:2.4.1.69]
References
Reactions
Displaying entries 1 - 10 of 12 in total
KEGG Reaction Enzyme Acceptor Product
R06086
R06156
R06170
R06089
R05968
R06027
R06090
R06024
R06035
R06031
Rhea

RHEA:50664

a β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl derivative + GDP-β-L-fucose
an α-L-Fuc-(1→2)-β-D-Gal-(1→3)-β-D-GlcNAc derivative + H+ + GDP
Enzyme
PMID

RHEA:32175

a β-D-Gal-(1→3)-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-β-D-Glc-(1↔1ʼ)-Cer(d18:1(4E)) + GDP-β-L-fucose
H+ + α-L-fucosyl-(1→2)- β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1ʼ)-N-acylsphing-4-enine + GDP
Enzyme
PMID

RHEA:50668

a β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl derivative + GDP-β-L-fucose
an α-L-Fuc-(1→2)-β-D-Gal-(1→4)-β-D-GlcNAc derivative + H+ + GDP
Enzyme
PMID
Ortholog
Displaying entries 1 - 10 of 34 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
2523 9606_1:004a56 HUMAN44869
14343 MOUSE55032
81919 RATNO17310
281174 BOVIN11468
718252 MACMU18098
100009291 RABIT18055
100171991 9601_0:004c08 PONAB15726
100389529 CALJA24553
100674697 LOXAF18112
100728677 CAVPO19345
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024