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fucosyltransferase 1

Summary

Gene Symbol

FUT1

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 468947
KEGG Gene ID: ptr:468947
PubChem: 468947

Annotation

Keyword

Glycoprotein
Glycosyltransferase
Golgi apparatus
Lipid metabolism
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9TUD6	Alpha(1,2)FT 1 Fucosyltransferase 1 GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1 Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT1 Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
positive regulation of sprouting angiogenesis
olfactory bulb development
regulation of endothelial cell proliferation
carbohydrate metabolic process	IEA	22301074 30032202
positive regulation of cell-matrix adhesion

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

glycosylation [inference]

fucosylation

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

developmental process [inference]

anatomical structure development [inference]

olfactory bulb development

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion

positive regulation of endothelial cell-matrix adhesion via fibronectin

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis [inference]

positive regulation of sprouting angiogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis [inference]

positive regulation of sprouting angiogenesis

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis [inference]

positive regulation of sprouting angiogenesis

regulation of sprouting angiogenesis [inference]

positive regulation of sprouting angiogenesis

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis [inference]

positive regulation of sprouting angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis [inference]

positive regulation of sprouting angiogenesis

regulation of sprouting angiogenesis [inference]

positive regulation of sprouting angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis [inference]

positive regulation of sprouting angiogenesis

regulation of cellular process [inference]

regulation of cell adhesion

regulation of cell-substrate adhesion [inference]

regulation of cell-matrix adhesion [inference]

positive regulation of cell-matrix adhesion

positive regulation of endothelial cell-matrix adhesion via fibronectin

regulation of endothelial cell-matrix adhesion via fibronectin [inference]

positive regulation of endothelial cell-matrix adhesion via fibronectin

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion

positive regulation of endothelial cell-matrix adhesion via fibronectin

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion

positive regulation of endothelial cell-matrix adhesion via fibronectin

regulation of cell population proliferation [inference]

regulation of epithelial cell proliferation [inference]

regulation of endothelial cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion

positive regulation of endothelial cell-matrix adhesion via fibronectin

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

regulation of multicellular organismal process [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis [inference]

positive regulation of sprouting angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis [inference]

positive regulation of sprouting angiogenesis

regulation of sprouting angiogenesis [inference]

positive regulation of sprouting angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis [inference]

positive regulation of sprouting angiogenesis

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IEA	22301074 30032202
Golgi cisterna membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

Golgi cisterna membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
alpha-(1,2)-fucosyltransferase activity
galactoside 2-alpha-L-fucosyltransferase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

fucosyltransferase activity [inference]

alpha-(1,2)-fucosyltransferase activity

galactoside 2-alpha-L-fucosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00718

Name

galactoside 2-L-fucosyltransferase 1/2 [EC:2.4.1.69]

References

Reactions

Displaying entries **1 - 10** of 12 in total

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KEGG Reaction	Enzyme	Acceptor	Product
R06085	2.4.1.69	G98726UE	G98900YM
R06156	2.4.1.69	G00049MO	G00050MO
R06089	2.4.1.69	G98726UE	G28261RX
R06086	2.4.1.69	G98900YM	G87164WU
R06090	2.4.1.69	G28261RX	G87164WU
R06035	2.4.1.69	G84034JH	G66427ZQ
R06170	2.4.1.69	G56390QA	G63238VS
R05968	2.4.1.69	G99053DY	G98465JN
R06024	2.4.1.69	G58896AZ	G13636IT
R06031	2.4.1.69	G64885AH	G58990QD

Rhea

RHEA:50668

a β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl derivative + GDP-β-L-fucose

an α-L-Fuc-(1→2)-β-D-Gal-(1→4)-β-D-GlcNAc derivative + H⁺ + GDP

Enzyme

2.4.1.344

PMID

RHEA:50664

a β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl derivative + GDP-β-L-fucose

an α-L-Fuc-(1→2)-β-D-Gal-(1→3)-β-D-GlcNAc derivative + H⁺ + GDP

Enzyme

2.4.1.69

PMID

RHEA:32175

a β-D-Gal-(1→3)-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-β-D-Glc-(1↔1ʼ)-Cer(d18:1(4E)) + GDP-β-L-fucose

H⁺ + α-L-fucosyl-(1→2)- β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1ʼ)-N-acylsphing-4-enine + GDP

Enzyme

2.4.1.69

PMID

Ortholog

Displaying entries **1 - 10** of 31 in total

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Species	Gene ID	Orthologous MAtrix
Callithrix jacchus	100389529	CALJA24553
Cercocebus atys	105595255	CERAT28506
Macaca mulatta	718252	MACMU18098
Macaca nemestrina	105478657	MACNE39747
Mandrillus leucophaeus	105539174	MANLE32646
Gorilla gorilla gorilla	101131113	GORGO14724
Pan paniscus	100990363	PANPA20959
Pongo abelii	100171991	PONAB15726
Homo sapiens	2523	HUMAN44869
Vulpes vulpes	112931221	VULVU26884