NADH:ubiquinone oxidoreductase core subunit S2

Summary
Gene Symbol
  • NDUFS2
Organism
Homo sapiens (human)
NCBI Gene
4720
PubChem
4720
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • 4Fe-4S
  • Acetylation
  • Alternative splicing
  • Disease variant
  • Leber hereditary optic neuropathy
  • Methylation
  • Mitochondrion inner membrane
  • NAD
  • Oxidoreductase
  • Reference proteome
  • Respiratory chain
  • Transit peptide
  • Translocase
  • Ubiquinone
Proteins
Displaying all 2 entries
UniProt Protein Name
O75306
  • Complex I-49kD
  • NADH-ubiquinone oxidoreductase 49 kDa subunit
B7Z792
  • Complex I-49kD
  • NADH-ubiquinone oxidoreductase 49 kDa subunit
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
NADH dehydrogenase
Functional Category
  • C: Energy production and conversion
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying all 5 entries
DO ID Disease Name Source
DOID:0112066 nuclear type mitochondrial complex I deficiency 6
DOID:11984 hypertrophic cardiomyopathy
DOID:2377 multiple sclerosis
DOID:3652 Leigh disease
DOID:655 inherited metabolic disorder

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: March 31, 2025