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neuropeptide Y receptor Y1

Summary

Gene Symbol

NPY1R

Organism

Homo sapiens (human)

External Links

NCBI Gene

4886

PubChem

4886

Alliance of Genome Resources

HGNC:7956

Annotation

Keyword

3D-structure
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P25929

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
outflow tract morphogenesis	IMP	19593212
sensory perception of pain	IEA
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	TAS	1317848
feeding behavior	IEA
locomotory behavior	IEA

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

neuropeptide signaling pathway

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of pain

behavior [inference]

developmental process [inference]

anatomical structure morphogenesis [inference]

outflow tract morphogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

regulation of developmental growth [inference]

regulation of multicellular organism growth

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of multicellular organism growth

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

neuropeptide signaling pathway

regulation of multicellular organismal process [inference]

regulation of multicellular organism growth

regulation of biological quality [inference]

regulation of blood pressure

Displaying **all 2** entries
GO Term	Evidence Code	PMID
neuron projection	IBA
plasma membrane	IBA TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
pancreatic polypeptide receptor activity	IEA
neuropeptide binding	IBA
neuropeptide Y receptor activity	TAS	1317848
neuropeptide receptor activity	IBA
protein binding	IPI	23597562

GO Hierarchy

molecular function

binding [inference]

protein binding

amide binding [inference]

peptide binding [inference]

neuropeptide binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

neuropeptide Y receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

neuropeptide Y receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying entries **1 - 10** of 13 in total

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DO ID	Disease Name	Source
DOID:0050742	nicotine dependence	Alliance of Genome Resources
DOID:0050830	peripheral artery disease	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:11832	visual epilepsy	Alliance of Genome Resources
DOID:1596	depressive disorder	Alliance of Genome Resources
DOID:1825	childhood absence epilepsy	Alliance of Genome Resources
DOID:2030	anxiety disorder	Alliance of Genome Resources
DOID:2559	opiate dependence	Alliance of Genome Resources
DOID:3328	temporal lobe epilepsy	Alliance of Genome Resources
DOID:670	amphetamine abuse	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	188742	WB:WBGene00020689
Caenorhabditis elegans	191160	WB:WBGene00013883
Petromyzon marinus	116940248		PETMA08602
Callorhinchus milii	103182253		CALMI24621
Latimeria chalumnae	102349584		LATCH05709
Danio rerio	793668	ZFIN:ZDB-GENE-080221-1	DANRE17013
Ictalurus punctatus	108260917		ICTPU23735
Chrysemys picta bellii	101936638		CHRPI11099
Crocodylus porosus	109309718		CROPO18429
Meleagris gallopavo	100550078		MELGA09636

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Acknowledgements