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neuropeptide Y receptor Y1

Summary

Gene Symbol

NPY1R

Organism

Homo sapiens (human)

External Links

NCBI Gene

4886

PubChem

4886

Alliance of Genome Resources

HGNC:7956

Annotation

Keyword

3D-structure
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P25929

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
glucose metabolic process	IEA
neuropeptide signaling pathway	IEA
regulation of multicellular organism growth	IEA
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	TAS	1321422
regulation of blood pressure	IEA

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

neuropeptide signaling pathway

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of pain

behavior [inference]

developmental process [inference]

anatomical structure morphogenesis [inference]

outflow tract morphogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

regulation of developmental growth [inference]

regulation of multicellular organism growth

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of multicellular organism growth

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

neuropeptide signaling pathway

regulation of multicellular organismal process [inference]

regulation of multicellular organism growth

regulation of biological quality [inference]

regulation of blood pressure

Displaying **all 2** entries
GO Term	Evidence Code	PMID
neuron projection	IBA
plasma membrane	IBA TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
pancreatic polypeptide receptor activity	IEA
neuropeptide binding	IBA
neuropeptide Y receptor activity	TAS	1317848
neuropeptide receptor activity	IBA
protein binding	IPI	23597562

GO Hierarchy

molecular function

binding [inference]

protein binding

amide binding [inference]

peptide binding [inference]

neuropeptide binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

neuropeptide Y receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

neuropeptide Y receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying entries **11 - 13** of 13 in total

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DO ID	Disease Name	Source
DOID:809	cocaine abuse	Alliance of Genome Resources
DOID:9970	obesity	Alliance of Genome Resources
DOID:9976	heroin dependence	Alliance of Genome Resources

Ortholog

Displaying entries **71 - 80** of 82 in total

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Species	Gene ID	Orthologous MAtrix
Sinocyclocheilus grahami	107548312	SINGR30998
Sinocyclocheilus grahami	107591578	SINGR49777
Equus asinus asinus	106837746	EQUAS05123
Chelonoidis abingdonii	116838044	CHEAB21293
Pteropus vampyrus	105294482	PTEVA11507
Propithecus coquereli	105811815	PROCO23379
Cyprinus carpio carpio	109081097	CYPCA28930
Cyprinus carpio carpio	109101734	CYPCA25603
Nannospalax galili	103745799	NANGA13502
Corvus moneduloides	116444365	CORMO21700

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Acknowledgements