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neuropeptide Y receptor Y1

Summary

Gene Symbol

NPY1R

Organism

Homo sapiens (human)

External Links

NCBI Gene

4886

PubChem

4886

Alliance of Genome Resources

HGNC:7956

Annotation

Keyword

3D-structure
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P25929

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
outflow tract morphogenesis	IMP	19593212
sensory perception of pain	IEA
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	TAS	1317848
feeding behavior	IEA
locomotory behavior	IEA

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

neuropeptide signaling pathway

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of pain

behavior [inference]

developmental process [inference]

anatomical structure morphogenesis [inference]

outflow tract morphogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

regulation of developmental growth [inference]

regulation of multicellular organism growth

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of multicellular organism growth

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

neuropeptide signaling pathway

regulation of multicellular organismal process [inference]

regulation of multicellular organism growth

regulation of biological quality [inference]

regulation of blood pressure

Displaying **all 2** entries
GO Term	Evidence Code	PMID
neuron projection	IBA
plasma membrane	IBA TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
pancreatic polypeptide receptor activity	IEA
neuropeptide binding	IBA
neuropeptide Y receptor activity	TAS	1317848
neuropeptide receptor activity	IBA
protein binding	IPI	23597562

GO Hierarchy

molecular function

binding [inference]

protein binding

amide binding [inference]

peptide binding [inference]

neuropeptide binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

neuropeptide Y receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

neuropeptide Y receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying entries **11 - 13** of 13 in total

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DO ID	Disease Name	Source
DOID:809	cocaine abuse	Alliance of Genome Resources
DOID:9970	obesity	Alliance of Genome Resources
DOID:9976	heroin dependence	Alliance of Genome Resources

Ortholog

Displaying entries **61 - 70** of 82 in total

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Species	Gene ID	Orthologous MAtrix
Jaculus jaculus	101616483	JACJA21639
Myotis lucifugus	102434231	MYOLU00552
Rhinolophus ferrumequinum	117037433	RHIFE14760
Taeniopygia guttata	100218761	TAEGU23553
Ficedula albicollis	101810357	FICAL05308
Chlorocebus sabaeus	103236468	CHLSB16771
Rhinopithecus bieti	108530882	RHIBE01906
Rhinopithecus roxellana	104672204	RHIRO16311
Nomascus leucogenys	100595787	NOMLE34601
Podarcis muralis	114604126	PODMU29666

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Acknowledgements