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solute carrier family 5 member 1

Summary

Gene Symbol

SLC5A1

Organism

Ovis aries (sheep)

External Links

NCBI Gene: 492300
KEGG Gene ID: oas:492300
PubChem: 492300

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Reference proteome
Sodium transport
Sugar transport
Symport
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A835ZR40	High affinity sodium-glucose cotransporter Solute carrier family 5 member 1
P53791	High affinity sodium-glucose cotransporter Solute carrier family 5 member 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
sodium ion transport	IEA	30032202
intestinal D-glucose absorption
transmembrane transport	IEA	22301074
transport across blood-brain barrier
sodium ion import across plasma membrane

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

glucose transmembrane transport [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

renal system process [inference]

renal absorption [inference]

renal glucose absorption

digestive system process [inference]

intestinal absorption [inference]

intestinal hexose absorption [inference]

intestinal D-glucose absorption

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

vascular transport [inference]

transport across blood-brain barrier

fluid transport [inference]

water transport [inference]

transepithelial water transport

epithelial fluid transport [inference]

transepithelial water transport

intestinal absorption [inference]

intestinal hexose absorption [inference]

intestinal D-glucose absorption

transmembrane transport

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

glucose transmembrane transport [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

transepithelial transport [inference]

epithelial fluid transport [inference]

transepithelial water transport

organic substance transport [inference]

water transport [inference]

transepithelial water transport

carbohydrate transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

glucose transmembrane transport [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

intestinal hexose absorption [inference]

intestinal D-glucose absorption

import into cell [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
early endosome
apical plasma membrane
plasma membrane	IEA	30032202
perinuclear region of cytoplasm

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

perinuclear region of cytoplasm

Displaying **all 4** entries
GO Term	Evidence Code	PMID
galactose:sodium symporter activity
alpha-glucoside transmembrane transporter activity
water transmembrane transporter activity
glucose:sodium symporter activity	IEA	30032202

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

carbohydrate transmembrane transporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

sugar transmembrane transporter activity [inference]

monosaccharide transmembrane transporter activity [inference]

hexose transmembrane transporter activity [inference]

galactose transmembrane transporter activity [inference]

galactose:sodium symporter activity

glucose transmembrane transporter activity [inference]

glucose:sodium symporter activity

inorganic molecular entity transmembrane transporter activity [inference]

water transmembrane transporter activity

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

carbohydrate derivative transmembrane transporter activity [inference]

glucoside transmembrane transporter activity [inference]

alpha-glucoside transmembrane transporter activity

salt transmembrane transporter activity [inference]

water transmembrane transporter activity

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

transporter

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Sodium/glucose symporter superfamily
Sodium/solute symporter

KEGG BRITE Database

Orthology

K14158

Name

solute carrier family 5 (sodium/glucose cotransporter), member 1

References

Ortholog

Displaying entries **1 - 10** of 92 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	6523		HUMAN60154
Mus musculus	20537		MOUSE43366
Rattus norvegicus	25552		RATNO08732
Bos taurus	282361	9913_0:0032df	BOVIN09896
Danio rerio	393654		DANRE00513
Sus scrofa	397113	9823_0:003ded	PIGXX07238
Pan troglodytes	458779		PANTR26407
Canis lupus familiaris	492299		CANLF10504
Macaca mulatta	717070		MACMU02524
Meleagris gallopavo	723986		MELGA04965