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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
opioid receptor kappa 1
Summary
- Gene Symbol
-
- OPRK1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Behavior
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Palmitate
- Proteomics identification
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P41145 |
|
| A0A5F9ZI09 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | ||
| maternal behavior | ||
| behavioral response to cocaine | ||
| estrous cycle | ||
| sensory perception of pain |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| axon terminus | ||
| synaptic vesicle membrane | ||
| membrane | ||
| postsynaptic membrane | ||
| T-tubule |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| neuropeptide binding | ||
| receptor serine/threonine kinase binding | ||
| dynorphin receptor activity | ||
| G protein-coupled opioid receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| neuropeptide binding |
| neuropeptide signaling pathway |
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050696 | fetal alcohol spectrum disorder | |
| DOID:0050741 | alcohol dependence | |
| DOID:0060001 | withdrawal disorder | |
| DOID:11206 | opioid abuse | |
| DOID:14330 | Parkinson's disease | |
| DOID:1574 | alcohol use disorder | |
| DOID:1596 | depressive disorder | |
| DOID:2559 | opiate dependence | |
| DOID:5844 | myocardial infarction | |
| DOID:6000 | congestive heart failure |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 18387 | MGI:97439 | MOUSE30386 | ||
| 29335 | RGD:69426 | RATNO34724 | ||
| 40019 | FB:FBgn0036789 | |||
| 360139 | ZFIN:ZDB-GENE-030729-1 | DANRE28724 | ||
| 472761 | 9598_0:002474 | PANTR42548 | ||
| 486951 | CANLF11640 | |||
| 540519 | BOVIN05823 | |||
| 710783 | MACMU43873 | |||
| 100023070 | MONDO19278 | |||
| 100084129 | ORNAN24213 |
