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3-oxoacid CoA-transferase 1

Summary

Gene Symbol

OXCT1

Aliases

SCOT
Succinyl-CoA:3-ketoacid-CoA transferase

Organism

Homo sapiens (human)

External Links

NCBI Gene

5019

HGNC

8527

KEGG Gene ID

hsa:5019

PubChem

5019

Alliance of Genome Resources

HGNC:8527

Annotation

Keyword

3D-structure
Alternative splicing
Direct protein sequencing
Disease variant
Lipid metabolism
Mitochondrion
Phosphoprotein
Reference proteome
Signal
Transferase
Transit peptide

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P55809	3-oxoacid CoA-transferase 1 Somatic-type succinyl-CoA:3-oxoacid CoA-transferase Succinyl-CoA:3-oxoacid CoA transferase
A0A024R040

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ketone catabolic process	IEA
cellular ketone body metabolic process	IBA IMP	9671268
ketone body catabolic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

small molecule catabolic process [inference]

organic substance catabolic process [inference]

lipid catabolic process [inference]

fatty acid derivative catabolic process [inference]

ketone body catabolic process

ketone catabolic process

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

ketone body metabolic process [inference]

ketone body catabolic process

cellular ketone metabolic process [inference]

ketone catabolic process

cellular catabolic process [inference]

cellular ketone body metabolic process

ketone body catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

fatty acid derivative catabolic process [inference]

ketone body catabolic process

fatty acid derivative metabolic process [inference]

fatty acid derivative catabolic process [inference]

ketone body catabolic process

ketone body metabolic process [inference]

ketone body catabolic process

small molecule metabolic process [inference]

cellular ketone metabolic process [inference]

ketone catabolic process

small molecule catabolic process [inference]

cellular ketone body metabolic process

ketone body catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

fatty acid derivative catabolic process [inference]

ketone body catabolic process

fatty acid derivative metabolic process [inference]

fatty acid derivative catabolic process [inference]

ketone body catabolic process

ketone body metabolic process [inference]

ketone body catabolic process

cellular ketone metabolic process [inference]

ketone catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

fatty acid derivative catabolic process [inference]

ketone body catabolic process

ketone catabolic process

cellular process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

ketone body metabolic process [inference]

ketone body catabolic process

cellular ketone metabolic process [inference]

ketone catabolic process

cellular catabolic process [inference]

cellular ketone body metabolic process

ketone body catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrion	HTP IBA IDA NAS	10964512 11756565 34800366
mitochondrial matrix	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying 1 entry
GO Term	Evidence Code	PMID
succinyl-CoA:3-oxo-acid CoA-transferase activity	IBA IMP	10964512 8751852

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring sulphur-containing groups [inference]

CoA-transferase activity [inference]

succinyl-CoA:3-oxo-acid CoA-transferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Succinyl-CoA:3-ketoacid coenzyme A transferase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
I: Lipid transport and metabolism

Displaying **all 4** entries
Gene Ontology
CoA-transferase activity
cellular ketone body metabolic process
ketone body catabolic process
transferase activity

Displaying **all 6** entries
InterPro
3-oxoacid CoA-transferase, subunit A
3-oxoacid CoA-transferase, subunit B
3-oxoacid CoA-transferase
Coenzyme A transferase active site
Coenzyme A transferase family I
NagB/RpiA transferase-like

Human Protein Atlas

ENSG00000083720