sirtuin 6

Summary
Gene Symbol
  • Sirt6
Organism
Mus musculus (house mouse)
NCBI Gene
50721
PubChem
50721
Alliance of Genome Resources
Annotation
Keyword
  • Acetylation
  • Acyltransferase
  • Chromatin regulator
  • DNA repair
  • DNA-binding
  • Developmental protein
  • Endoplasmic reticulum
  • Glycosyltransferase
  • Isopeptide bond
  • Metal-binding
  • NAD
  • Nucleotidyltransferase
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • RNA-binding
  • Reference proteome
  • Telomere
  • Tumor suppressor
  • Ubl conjugation
  • Zinc
Proteins
Displaying all 2 entries
UniProt Protein Name
Q3UKP1
  • NAD-dependent protein deacetylase sirtuin-6
  • Protein mono-ADP-ribosyltransferase sirtuin-6
P59941
  • NAD-dependent protein deacetylase sirtuin-6
  • Protein mono-ADP-ribosyltransferase sirtuin-6
  • Regulatory protein SIR2 homolog 6
  • SIR2-like protein 6
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
NAD-dependent protein deacetylase
Functional Category
  • J: Translation, ribosomal structure and biogenesis
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:3911 progeria

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026