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sirtuin 6

Summary

Gene Symbol

Sirt6

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

50721

PubChem

50721

Alliance of Genome Resources

MGI:1354161

Annotation

Keyword

Acetylation
Acyltransferase
Chromatin regulator
DNA repair
DNA-binding
Developmental protein
Endoplasmic reticulum
Glycosyltransferase
Isopeptide bond
Metal-binding
NAD
Nucleotidyltransferase
Nucleus
Phosphoprotein
Proteomics identification
RNA-binding
Reference proteome
Telomere
Transferase
Tumor suppressor
Ubl conjugation
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P59941	NAD-dependent protein deacetylase sirtuin-6 Protein mono-ADP-ribosyltransferase sirtuin-6 Regulatory protein SIR2 homolog 6 SIR2-like protein 6
Q3UKP1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **21 - 25** of 53 in total

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GO Term	Evidence Code	PMID
protein delipidation	ISO ISS
positive regulation of chondrocyte proliferation	IEA ISO
protein localization to site of double-strand break	IEA ISO
negative regulation of transcription by RNA polymerase II	IBA IMP ISO	28355567 31399344
protein destabilization	IMP ISO ISS	20141841

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein deacylation [inference]

protein deacetylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

ketone biosynthetic process

small molecule biosynthetic process [inference]

ketone biosynthetic process

organic substance biosynthetic process [inference]

ketone biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

cellular ketone metabolic process [inference]

ketone biosynthetic process

cellular biosynthetic process [inference]

ketone biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

protein metabolic process [inference]

protein modification process [inference]

protein deacylation [inference]

protein deacetylation

small molecule metabolic process [inference]

cellular ketone metabolic process [inference]

ketone biosynthetic process

small molecule biosynthetic process [inference]

ketone biosynthetic process

organic substance metabolic process [inference]

cellular ketone metabolic process [inference]

ketone biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein deacylation [inference]

protein deacetylation

macromolecule modification [inference]

protein modification process [inference]

protein deacylation [inference]

protein deacetylation

macromolecule deacylation [inference]

protein deacylation [inference]

protein deacetylation

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein deacylation [inference]

protein deacetylation

organic substance biosynthetic process [inference]

ketone biosynthetic process

cellular process [inference]

cell growth [inference]

developmental cell growth [inference]

post-embryonic cardiac muscle cell growth involved in heart morphogenesis

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

cellular ketone metabolic process [inference]

ketone biosynthetic process

cellular biosynthetic process [inference]

ketone biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

cellular developmental process [inference]

cell differentiation [inference]

cardiocyte differentiation [inference]

cardiac muscle cell differentiation

muscle cell differentiation [inference]

striated muscle cell differentiation [inference]

cardiac muscle cell differentiation

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to site of double-strand break

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

heterochromatin organization [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

DNA repair-dependent chromatin remodeling

multicellular organismal process [inference]

determination of adult lifespan

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

cardiocyte differentiation [inference]

cardiac muscle cell differentiation

muscle cell differentiation [inference]

striated muscle cell differentiation [inference]

cardiac muscle cell differentiation

growth [inference]

cell growth [inference]

developmental cell growth [inference]

post-embryonic cardiac muscle cell growth involved in heart morphogenesis

developmental growth [inference]

developmental cell growth [inference]

post-embryonic cardiac muscle cell growth involved in heart morphogenesis

developmental growth involved in morphogenesis [inference]

growth involved in heart morphogenesis [inference]

post-embryonic cardiac muscle cell growth involved in heart morphogenesis

homeostatic process [inference]

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

rhythmic process [inference]

circadian rhythm [inference]

circadian regulation of gene expression

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

response to UV

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to site of double-strand break

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to site of double-strand break

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gluconeogenesis

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

circadian regulation of gene expression

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gluconeogenesis

regulation of carbohydrate biosynthetic process [inference]

regulation of gluconeogenesis [inference]

negative regulation of gluconeogenesis

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gluconeogenesis

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gluconeogenesis

negative regulation of cellular catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular senescence

negative regulation of carbohydrate metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of small molecule metabolic process [inference]

negative regulation of gluconeogenesis

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of cold-induced thermogenesis

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of cellular catabolic process [inference]

regulation of nucleotide catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of cellular catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of carbohydrate catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

regulation of lipid catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of ATP metabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of double-strand break repair [inference]

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gluconeogenesis

negative regulation of cellular catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular senescence

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

circadian regulation of gene expression

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gluconeogenesis

regulation of cellular catabolic process [inference]

regulation of nucleotide catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of cellular catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

regulation of generation of precursor metabolites and energy [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of phosphate metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of ATP metabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of phosphate metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of cellular senescence [inference]

negative regulation of cellular senescence

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of ATP metabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of double-strand break repair [inference]

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteolysis involved in protein catabolic process [inference]

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

circadian regulation of gene expression

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of double-strand break repair [inference]

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteolysis involved in protein catabolic process [inference]

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of small molecule metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of ATP metabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of glucose metabolic process [inference]

regulation of gluconeogenesis [inference]

negative regulation of gluconeogenesis

negative regulation of small molecule metabolic process [inference]

negative regulation of gluconeogenesis

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of glucose metabolic process [inference]

regulation of gluconeogenesis [inference]

negative regulation of gluconeogenesis

regulation of carbohydrate biosynthetic process [inference]

regulation of gluconeogenesis [inference]

negative regulation of gluconeogenesis

regulation of carbohydrate catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of carbohydrate metabolic process [inference]

regulation of lipid metabolic process

regulation of lipid catabolic process

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of ATP metabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of double-strand break repair [inference]

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteolysis involved in protein catabolic process [inference]

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of cold-induced thermogenesis [inference]

positive regulation of cold-induced thermogenesis

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of nucleocytoplasmic transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

regulation of transmembrane transport [inference]

regulation of glucose transmembrane transport [inference]

negative regulation of glucose transmembrane transport [inference]

negative regulation of glucose import

regulation of glucose import [inference]

negative regulation of glucose import

negative regulation of transmembrane transport [inference]

negative regulation of glucose transmembrane transport [inference]

negative regulation of glucose import

regulation of secretion [inference]

regulation of peptide secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

regulation of protein secretion

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

negative regulation of transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of transmembrane transport [inference]

negative regulation of glucose transmembrane transport [inference]

negative regulation of glucose import

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of protein secretion

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of peptide transport [inference]

regulation of peptide secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of nucleocytoplasmic transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of protein secretion

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

regulation of protein localization to nucleus [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of protein localization to nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of protein localization [inference]

negative regulation of protein localization to chromatin

negative regulation of protein localization to nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

positive regulation of protein localization [inference]

positive regulation of protein localization to chromatin

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane

regulation of protein localization to chromatin [inference]

regulation of circadian rhythm

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of cold-induced thermogenesis

positive regulation of signaling [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

positive regulation of epithelial cell proliferation [inference]

positive regulation of endothelial cell proliferation [inference]

positive regulation of vascular endothelial cell proliferation

positive regulation of cell communication [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of cell differentiation [inference]

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of protein localization [inference]

positive regulation of protein localization to chromatin

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of response to stimulus [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of stem cell population maintenance

positive regulation of vasculature development [inference]

positive regulation of angiogenesis [inference]

positive regulation of blood vessel branching

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of blood vessel branching

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis [inference]

positive regulation of blood vessel branching

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gluconeogenesis

negative regulation of catabolic process [inference]

negative regulation of cellular catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gluconeogenesis

negative regulation of cellular catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular senescence

negative regulation of carbohydrate metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of small molecule metabolic process [inference]

negative regulation of gluconeogenesis

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gluconeogenesis

negative regulation of cellular catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular senescence

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of transmembrane transport [inference]

negative regulation of glucose transmembrane transport [inference]

negative regulation of glucose import

negative regulation of protein localization [inference]

negative regulation of protein localization to chromatin

negative regulation of protein localization to nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of transmembrane transport [inference]

negative regulation of glucose transmembrane transport [inference]

negative regulation of glucose import

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of double-strand break repair [inference]

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis [inference]

positive regulation of blood vessel branching

regulation of blood vessel branching [inference]

positive regulation of blood vessel branching

regulation of morphogenesis of a branching structure [inference]

regulation of blood vessel branching [inference]

positive regulation of blood vessel branching

regulation of morphogenesis of an epithelium [inference]

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of blood vessel branching

regulation of blood vessel branching [inference]

positive regulation of blood vessel branching

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

regulation of fat cell differentiation [inference]

positive regulation of fat cell differentiation

regulation of stem cell differentiation [inference]

positive regulation of stem cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of stem cell population maintenance

positive regulation of vasculature development [inference]

positive regulation of angiogenesis [inference]

positive regulation of blood vessel branching

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of blood vessel branching

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis [inference]

positive regulation of blood vessel branching

regulation of blood vessel branching [inference]

positive regulation of blood vessel branching

positive regulation of vasculature development [inference]

positive regulation of angiogenesis [inference]

positive regulation of blood vessel branching

regulation of stem cell population maintenance [inference]

positive regulation of stem cell population maintenance

regulation of cellular process [inference]

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of ATP metabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of double-strand break repair [inference]

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gluconeogenesis

negative regulation of cellular catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular senescence

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

circadian regulation of gene expression

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA-templated transcription elongation [inference]

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

regulation of transcription elongation by RNA polymerase II [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gluconeogenesis

regulation of cellular catabolic process [inference]

regulation of nucleotide catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of cellular catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

regulation of generation of precursor metabolites and energy [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of phosphate metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide catabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of ATP metabolic process [inference]

regulation of glycolytic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of phosphate metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

regulation of cellular senescence [inference]

negative regulation of cellular senescence

regulation of transmembrane transport [inference]

regulation of glucose transmembrane transport [inference]

negative regulation of glucose transmembrane transport [inference]

negative regulation of glucose import

regulation of glucose import [inference]

negative regulation of glucose import

negative regulation of transmembrane transport [inference]

negative regulation of glucose transmembrane transport [inference]

negative regulation of glucose import

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

positive regulation of epithelial cell proliferation [inference]

positive regulation of endothelial cell proliferation [inference]

positive regulation of vascular endothelial cell proliferation

negative regulation of cell population proliferation

regulation of fibroblast proliferation [inference]

positive regulation of fibroblast proliferation

regulation of epithelial cell proliferation [inference]

regulation of endothelial cell proliferation [inference]

positive regulation of endothelial cell proliferation [inference]

positive regulation of vascular endothelial cell proliferation

regulation of vascular endothelial cell proliferation [inference]

positive regulation of vascular endothelial cell proliferation

positive regulation of epithelial cell proliferation [inference]

positive regulation of endothelial cell proliferation [inference]

positive regulation of vascular endothelial cell proliferation

regulation of stem cell proliferation [inference]

positive regulation of stem cell proliferation

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

regulation of fat cell differentiation [inference]

positive regulation of fat cell differentiation

regulation of stem cell differentiation [inference]

positive regulation of stem cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

positive regulation of epithelial cell proliferation [inference]

positive regulation of endothelial cell proliferation [inference]

positive regulation of vascular endothelial cell proliferation

positive regulation of cell communication [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of cell differentiation [inference]

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of protein localization [inference]

positive regulation of protein localization to chromatin

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of gluconeogenesis

negative regulation of cellular catabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleotide metabolic process [inference]

negative regulation of nucleotide catabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of purine nucleotide metabolic process [inference]

negative regulation of purine nucleotide catabolic process [inference]

negative regulation of glycolytic process

negative regulation of ATP metabolic process [inference]

negative regulation of glycolytic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription, elongation [inference]

negative regulation of transcription elongation by RNA polymerase II

negative regulation of cellular senescence

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of transmembrane transport [inference]

negative regulation of glucose transmembrane transport [inference]

negative regulation of glucose import

negative regulation of protein localization [inference]

negative regulation of protein localization to chromatin

negative regulation of protein localization to nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

regulation of chromosome organization [inference]

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of nucleocytoplasmic transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein import into nucleus

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

regulation of protein secretion

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

regulation of protein localization to nucleus [inference]

regulation of protein import into nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of protein localization to nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of protein localization [inference]

negative regulation of protein localization to chromatin

negative regulation of protein localization to nucleus [inference]

negative regulation of protein import into nucleus

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein import into nucleus

positive regulation of protein localization [inference]

positive regulation of protein localization to chromatin

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane

regulation of protein localization to chromatin [inference]

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair

regulation of double-strand break repair [inference]

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

regulation of protein secretion

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

positive regulation of protein secretion [inference]

positive regulation of insulin secretion

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis [inference]

positive regulation of blood vessel branching

regulation of morphogenesis of a branching structure [inference]

regulation of blood vessel branching [inference]

positive regulation of blood vessel branching

regulation of cold-induced thermogenesis [inference]

positive regulation of cold-induced thermogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis [inference]

positive regulation of blood vessel branching

regulation of blood vessel branching [inference]

positive regulation of blood vessel branching

positive regulation of vasculature development [inference]

positive regulation of angiogenesis [inference]

positive regulation of blood vessel branching

regulation of stem cell population maintenance [inference]

positive regulation of stem cell population maintenance

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

positive regulation of insulin secretion

positive regulation of peptide hormone secretion [inference]

positive regulation of insulin secretion

regulation of protein stability [inference]

protein destabilization

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GO Term	Evidence Code	PMID
pericentric heterochromatin	IEA ISO
site of double-strand break	IEA ISO
intracellular membrane-bounded organelle	ISO
nucleoplasm	ISO ISS TAS
chromatin	IDA ISO ISS	31399344

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-DNA complex [inference]

chromatin

heterochromatin [inference]

pericentric heterochromatin

cellular anatomical entity [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular non-membrane-bounded organelle [inference]

nucleolus

site of DNA damage

site of double-strand break

chromosomal region [inference]

chromosome, telomeric region [inference]

chromosome, subtelomeric region

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
nucleosome binding	ISO ISS
zinc ion binding	ISS
NAD-dependent protein deacetylase activity	IDA ISO	27457971 30782483 31442424 31851938
NAD+-protein ADP-ribosyltransferase activity	IDA ISO	25247314 31216030
chromatin binding	IDA ISO	24105743

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

glycosyltransferase activity [inference]

pentosyltransferase activity [inference]

NAD+-protein ADP-ribosyltransferase activity

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity

hydrolase activity [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [inference]

histone deacetylase activity [inference]

NAD-dependent histone deacetylase activity

histone H3K deacetylase activity [inference]

histone H3K9 deacetylase activity [inference]

NAD-dependent histone H3K9 deacetylase activity

deacetylase activity [inference]

protein lysine deacetylase activity

histone deacetylase activity [inference]

NAD-dependent histone deacetylase activity

histone H3K deacetylase activity [inference]

histone H3K9 deacetylase activity [inference]

NAD-dependent histone H3K9 deacetylase activity

NAD-dependent protein deacetylase activity

NAD-dependent histone deacetylase activity

catalytic activity, acting on a protein [inference]

protein lysine deacetylase activity

histone deacetylase activity [inference]

NAD-dependent histone deacetylase activity

histone H3K deacetylase activity [inference]

histone H3K9 deacetylase activity [inference]

NAD-dependent histone H3K9 deacetylase activity

NAD-dependent protein deacetylase activity

NAD-dependent histone deacetylase activity

histone modifying activity [inference]

histone deacetylase activity [inference]

NAD-dependent histone deacetylase activity

histone H3K deacetylase activity [inference]

histone H3K9 deacetylase activity [inference]

NAD-dependent histone H3K9 deacetylase activity

NAD+-protein ADP-ribosyltransferase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding [inference]

NAD+ binding

ion binding [inference]

anion binding [inference]

NAD+ binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

protein-containing complex binding [inference]

chromatin binding

TORC2 complex binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

RNA binding [inference]

lncRNA binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding [inference]

NAD+ binding

transcription regulator activity [inference]

transcription coregulator activity [inference]

transcription corepressor activity

small molecule sensor activity [inference]

DNA damage sensor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

NAD-dependent protein deacylase sirtuin-6

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

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Gene Ontology
DNA damage sensor activity
DNA repair-dependent chromatin remodeling
NAD+ binding
NAD+-protein ADP-ribosyltransferase activity
NAD-dependent histone H3K18 deacetylase activity
NAD-dependent histone H3K56 deacetylase activity
NAD-dependent histone H3K9 deacetylase activity
NAD-dependent histone deacetylase activity
NAD-dependent protein deacetylase activity
NAD-dependent protein demyristoylase activity

Displaying **all 3** entries
InterPro
DHS-like NAD/FAD-binding domain superfamily
Sirtuin family, catalytic core domain
Sirtuin family

Rhea

RHEA:43636

H₂O + NAD⁺

nicotinamide + 2''-O-acetyl-ADP-D-ribose

Enzyme

2.3.1.286

PMID

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0080208	metabolic dysfunction-associated steatotic liver disease	Alliance of Genome Resources
DOID:224	transient cerebral ischemia	Alliance of Genome Resources
DOID:3911	progeria	Alliance of Genome Resources
DOID:9970	obesity	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	41254		FB:FBgn0037802
Homo sapiens	51548		HGNC:14934	HUMAN39833
Caenorhabditis elegans	182284		WB:WBGene00004803
Rattus norvegicus	299638	10116_1:002a52	RGD:1305216	RATNO37482
Xenopus tropicalis	394980		Xenbase:XB-GENE-5929105
Danio rerio	415161		ZFIN:ZDB-GENE-031007-2	DANRE30231
Canis lupus familiaris	485045			CANLF08018
Bos taurus	535416			BOVIN32892
Macaca mulatta	714545			MACMU20515
Pan troglodytes	737026			PANTR16808

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements