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alpha-1,4-N-acetylglucosaminyltransferase

Summary

Gene Symbol

A4GNT

Aliases

alpha4GnT

Organism

Homo sapiens (human)

External Links

NCBI Gene

51146

GGDB ID

gg124

HGNC

17968

mRNA

NM_016161

map

3p14.3

Protein

NP_057245

OMIM

616709

KEGG Gene ID

hsa:51146

PubChem

51146

Alliance of Genome Resources

HGNC:17968

Annotation

Keyword

Glycoprotein
Glycosyltransferase
Golgi apparatus
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UNA3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
carbohydrate metabolic process	TAS	10430883
protein O-linked glycosylation	IBA
glycoprotein biosynthetic process	IDA	10430883
O-glycan processing	TAS
epithelial cell proliferation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing

organic substance metabolic process [inference]

carbohydrate metabolic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process

cellular process [inference]

cell population proliferation [inference]

epithelial cell proliferation

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation

regulation of epithelial cell proliferation [inference]

negative regulation of epithelial cell proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
Golgi membrane	TAS
membrane	TAS	10430883

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
acetylglucosaminyltransferase activity	TAS
acetylglucosaminyltransferase activity	IDA	10430883
acetylglucosaminyltransferase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

lariat debranching enzyme a

Functional Category

G: Carbohydrate transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
RNA lariat debranching enzyme activity
hydrolase activity, acting on ester bonds
hydrolase activity
mRNA processing
metal ion binding

Displaying **all 4** entries
InterPro
Calcineurin-like phosphoesterase domain, ApaH type
Lariat debranching enzyme, C-terminal
Lariat debranching enzyme, N-terminal metallophosphatase domain
Metallo-dependent phosphatase-like

GlycoGene Database (GGDB)

GGDB ID

gg124

Gene Symbol

A4GNT

Reactions

Displaying 1 entry
Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
(not applicable)	G65889KE	R	G94473FP	R	10430883

Displaying entries **1 - 5** of 10 in total

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Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
(not applicable)	G65889KE	R	G94473FP	R	10430883
UDP-GlcNAc	G39890DX	[alpha]pNP	G34764BK	[alpha]pNP	10430883
UDP-GlcNAc	G64973KT	[alpha]pNP	G39890DX	[alpha]pNP	10430883
UDP-GlcNAc	G32910OR	[alpha]pNP	G34764BK	[alpha]pNP	10430883
UDP-GlcNAc	G64973KT	[alpha]pNP	G34764BK	[alpha]pNP	10430883

Displaying **all 4** entries
Donor	Acceptor	Reducing terminal(Acceptor)	Reference
UDP-GlcNAc	G57321FI	[alpha]pNP	10430883
UDP-GlcNAc	G00035MO	pNP	10430883
UDP-GlcNAc	G65889KE	[alpha]pNP	10430883
UDP-GlcNAc	G65889KE	[beta]pNP	10430883

Orthologous Gene

Displaying **all 2** entries
Species	Protein	mRNA
Rattus norvegicus	XP_236601	XM_236601
Mus musculus	XP_286168	XM_286168

KEGG BRITE Database

Orthology

K08251

Name

alpha 1,4-N-acetylglucosaminyltransferase [EC:2.4.1.-]

References

10430883

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R07131	2.4.1.-	G09938IH	G05724WC

Ortholog

Displaying entries **11 - 20** of 72 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Rattus norvegicus	685758	Xenbase:XB-GENE-991165	RATNO39821
Macaca mulatta	716512		MACMU27938
Macaca mulatta	716551		MACMU27938
Xenopus tropicalis	734685	Xenbase:XB-GENE-5796041
Monodelphis domestica	100024221		MONDO21204
Equus caballus	100033872		HORSE11585
Ornithorhynchus anatinus	100091228		ORNAN11411
Oryctolagus cuniculus	100351085		RABIT04407
Callithrix jacchus	100393849		CALJA14680
Pongo abelii	100462185		PONAB26431

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

GlycoGene Database (GGDB)

KEGG BRITE Database

International Collaboration

Acknowledgements