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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
acyl-CoA oxidase 1
Summary
- Gene Symbol
-
- ACOX1
- Aliases
-
- PALMCOX
- palmitoyl-CoA oxidase
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- Deafness
- Disease variant
- FAD
- Fatty acid metabolism
- Neuropathy
- Oxidoreductase
- Peroxisome
- Phosphoprotein
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| Q15067 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| hydrogen peroxide biosynthetic process | ||
| fatty acid beta-oxidation using acyl-CoA oxidase | ||
| spermatogenesis | ||
| fatty acid catabolic process | ||
| lipid metabolic process |
GO Hierarchy
biological process
metabolic process [inference]
catabolic process [inference]
cellular metabolic process [inference]
primary metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytosol |
|
|
| membrane | ||
| peroxisome | ||
| peroxisomal membrane | ||
| peroxisomal matrix |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| FAD binding | ||
| palmitoyl-CoA oxidase activity |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11830 | myopia | |
| DOID:11832 | visual epilepsy | |
| DOID:12139 | dysthymic disorder | |
| DOID:1289 | neurodegenerative disease | |
| DOID:13174 | dissociated nystagmus | |
| DOID:13714 | anodontia | |
| DOID:14221 | abdominal obesity-metabolic syndrome 1 | |
| DOID:1470 | major depressive disorder | |
| DOID:1595 | melancholic depression | |
| DOID:1596 | depressive disorder |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000248 | Brachycephaly |
| HP:0000286 | Epicanthus |
| HP:0000316 | Hypertelorism |
| HP:0000369 | Low-set ears |
| HP:0000407 | Sensorineural hearing impairment |
| HP:0000431 | Wide nasal bridge |
| HP:0000486 | Strabismus |
| HP:0000510 | Rod-cone dystrophy |
| Disease ID | Disease Name |
|---|---|
| ORPHA:2971 |
|
| OMIM:264470 |
|
| OMIM:618960 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP002411
- Gene Name
- acyl-CoA oxidase 1, palmitoyl
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 101166187 | ORYLA00070 | ||
| 100707091 | ORENI61337 | ||
| 115583576 | SPAAU57174 | ||
| 403357 | Xenbase:XB-GENE-17332128 | ||
| 735228 | Xenbase:XB-GENE-1008083 | ||
| 548479 | Xenbase:XB-GENE-1008078 | ||
| 101943673 | CHRPI01854 | ||
| 109315088 | CROPO19767 | ||
| 113437161 | PSETE08329 | ||
| 100540963 | MELGA06633 |
