phosphatidylinositol glycan anchor biosynthesis class F

Summary
Gene Symbol
  • PIGF
Aliases
  • PIG-F
Organism
Homo sapiens (human)
External Links
NCBI Gene
5281
GGDB ID
HGNC
8962
mRNA
map
  • 2p21-p16, 2p21 (OMIM)
Protein
OMIM
KEGG Gene ID
hsa:5281
PubChem
5281
Alliance of Genome Resources
Annotation
Keyword
  • Alternative splicing
  • Disease variant
  • Endoplasmic reticulum
  • Epilepsy
  • GPI-anchor biosynthesis
  • Intellectual disability
  • Reference proteome
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
Q6IB04
Q07326
  • GPI11 homolog
Gene Ontology (GO)
Displaying 1 entry
GO Term Evidence Code PMID
GPI anchor biosynthetic process
GO Hierarchy
GlycoGene Database (GGDB)
GGDB ID
gg228
Gene Symbol
  • PIGF
KEGG BRITE Database
Orthology
K05287
Name
GPI ethanolamine phosphate transferase 2/3 subunit F
References
Reactions
Displaying all 2 entries
KEGG Reaction Enzyme Acceptor Product
R05924
R08107
Disease
Disease Ontology
Displaying entries 11 - 20 of 27 in total
DO ID Disease Name Source
DOID:3095 germ cell and embryonal cancer
DOID:3304 germinoma
DOID:3347 osteosarcoma
DOID:3376 bone osteosarcoma
DOID:3393 coronary artery disease
DOID:3891 placental insufficiency
DOID:4647 trilateral retinoblastoma
DOID:4648 familial retinoblastoma
DOID:468 intramuscular hemangioma
DOID:474 histiocytoid hemangioma
The Human Phenotype Ontology
Displaying entries 21 - 28 of 28 in total
HPO ID HPO Term
HP:0004379 Abnormality of alkaline phosphatase level
HP:0005707 Bilateral triphalangeal thumbs
HP:0008398 Hypoplastic fifth fingernail
HP:0009882 Short distal phalanx of finger
HP:0010864 Intellectual disability, severe
HP:0012168 Head-banging
HP:0012553 Hypoplastic thumbnail
HP:0200105 Absent fifth toenail
Displaying 1 entry
Disease ID Disease Name
OMIM:619356
  • onychodystrophy, osteodystrophy, impaired intellectual development, and seizures syndrome
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP002127
Gene Name
phosphatidylinositol glycan anchor biosynthesis, class F

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024