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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
nucleobindin 2
Summary
- Gene Symbol
-
- Nucb2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Calcium
- Cleavage on pair of basic residues
- Cytoplasm
- DNA-binding
- Endoplasmic reticulum
- Golgi apparatus
- Guanine-nucleotide releasing factor
- Membrane
- Metal-binding
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Signal
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of fatty acid oxidation | ||
| negative regulation of insulin receptor signaling pathway | ||
| insulin metabolic process | ||
| positive regulation of testosterone secretion | ||
| sequestering of metal ion |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi medial cisterna | ||
| Golgi apparatus | ||
| perikaryon | ||
| extracellular region | ||
| nuclear outer membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA binding | ||
| tumor necrosis factor receptor binding | ||
| G-protein alpha-subunit binding | ||
| guanyl-nucleotide exchange factor activity | ||
| calcium ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Nucleobindin
- Functional Category
-
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| calcium ion binding |
| metal ion binding |
| InterPro |
|---|
| EF-Hand 1, calcium-binding site |
| EF-hand domain pair |
| EF-hand domain |
| Nucleobindin |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050741 | alcohol dependence | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9970 | obesity |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 4925 | HGNC:8044 | HUMAN04822 | ||
| 39978 | FB:FBgn0052190 | |||
| 59295 | 10116_1:000903 | RGD:620888 | RATNO16098 | |
| 326050 | ZFIN:ZDB-GENE-030131-4775 | DANRE14128 | ||
| 373078 | ZFIN:ZDB-GENE-030826-14 | DANRE41067 | ||
| 476876 | CANLF08573 | |||
| 509003 | BOVIN06679 | |||
| 548541 | Xenbase:XB-GENE-485477 | |||
| 697084 | MACMU09405 | |||
| 748720 | PANTR02394 |
