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nucleobindin 2
Summary
- Gene Symbol
-
- Nucb2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Calcium
- Cleavage on pair of basic residues
- Cytoplasm
- DNA-binding
- Endoplasmic reticulum
- Golgi apparatus
- Guanine-nucleotide releasing factor
- Membrane
- Metal-binding
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Signal
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of fatty acid oxidation | ||
| negative regulation of insulin receptor signaling pathway | ||
| insulin metabolic process | ||
| positive regulation of testosterone secretion | ||
| sequestering of metal ion |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi medial cisterna | ||
| Golgi apparatus | ||
| perikaryon | ||
| extracellular region | ||
| nuclear outer membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA binding | ||
| tumor necrosis factor receptor binding | ||
| G-protein alpha-subunit binding | ||
| guanyl-nucleotide exchange factor activity | ||
| calcium ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Nucleobindin
- Functional Category
-
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| calcium ion binding |
| metal ion binding |
| InterPro |
|---|
| EF-Hand 1, calcium-binding site |
| EF-hand domain pair |
| EF-hand domain |
| Nucleobindin |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050741 | alcohol dependence | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9970 | obesity |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100600078 | NOMLE09920 | |||
| 100671470 | LOXAF12506 | |||
| 100696340 | ORENI33381 | |||
| 100717348 | 10141_0:001562 | CAVPO19070 | ||
| 100754356 | 10029_0:002486 | CRIGR24234 | ||
| 100924777 | SARHA00944 | |||
| 100966072 | OTOGA19334 | |||
| 100979598 | PANPA06251 | |||
| 101011608 | PAPAN05889 | |||
| 101071051 | TAKRU08392 |
