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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
toll like receptor 9
Summary
- Gene Symbol
-
- TLR9
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cytoplasmic vesicle
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Golgi apparatus
- Inflammatory response
- Innate immunity
- Leucine-rich repeat
- Lysosome
- Palmitate
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9NR96 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| microglial cell activation | ||
| positive regulation of granulocyte macrophage colony-stimulating factor production | ||
| positive regulation of tumor necrosis factor production | ||
| cellular response to chloroquine | ||
| positive regulation of interleukin-6 production |
GO Hierarchy
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of intestinal epithelial cell development
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of intestinal epithelial cell development
biological process
immune system process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of transport [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of response to stimulus [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
regulation of signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of response to stress [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of transmembrane transport [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cell activation [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| apical plasma membrane | ||
| endoplasmic reticulum membrane | ||
| plasma membrane | ||
| endosome | ||
| endolysosome |
| GO Term | Evidence Code | PMID |
|---|---|---|
| unmethylated CpG binding | ||
| interleukin-1 receptor binding | ||
| siRNA binding | ||
| pattern recognition receptor activity | ||
| protein homodimerization activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Twinfilin
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| ADF-H/Gelsolin-like domain superfamily |
| Actin-depolymerising factor homology domain |
| Twinfilin |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050127 | sinusitis | |
| DOID:0080162 | lupus nephritis | |
| DOID:0080208 | metabolic dysfunction-associated steatotic liver disease | |
| DOID:0080998 | acute necrotizing pancreatitis | |
| DOID:10223 | dermatomyositis | |
| DOID:10533 | viral pneumonia | |
| DOID:10690 | mastitis | |
| DOID:11166 | Human papillomavirus infectious disease | |
| DOID:11168 | anogenital venereal wart | |
| DOID:11204 | allergic conjunctivitis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 81897 | MGI:1932389 | MOUSE60630 | ||
| 282602 | BOVIN17719 | |||
| 338457 | RGD:631352 | RATNO40494 | ||
| 397007 | PIGXX04207 | |||
| 403128 | ZFIN:ZDB-GENE-040219-10 | |||
| 403502 | CANLF07441 | |||
| 470827 | 9598_0:0012de | PANTR31285 | ||
| 493839 | FELCA03744 | |||
| 494547 | SHEEP08388 | |||
| 574395 | MACMU30304 |
