GlyCosmos Portal

Annotation

Keyword

3D-structure
4Fe-4S
DNA excision
DNA repair
DNA replication
DNA-binding
DNA-directed DNA polymerase
Disease variant
Exonuclease
Isopeptide bond
Methylation
Nucleus
Proteomics identification
Reference proteome
Ubl conjugation
Zinc-finger

Proteins

Displaying **all 5** entries
UniProt	Protein Name
P28340	3'-5' exodeoxyribonuclease DNA polymerase subunit delta p125
M0R2B7
Q59FA0
A0A087WYJ2
Q308M6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
fatty acid homeostasis	IMP	23770608
DNA-templated DNA replication	IBA IDA	20334433
DNA replication	IMP	16762037
DNA replication proofreading	IBA
DNA repair	TAS	3146346

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

fatty acid homeostasis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

response to UV

cellular response to UV

cellular response to light stimulus [inference]

cellular response to UV

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
aggresome	IDA
nucleus	IDA	16762037
nucleotide-excision repair complex	IDA	20713449
nucleoplasm	IDA TAS
cytosol	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

intracellular protein-containing complex [inference]

DNA polymerase complex [inference]

delta DNA polymerase complex

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

DNA polymerase complex [inference]

delta DNA polymerase complex

cellular anatomical entity [inference]

intracellular anatomical structure [inference]

inclusion body [inference]

aggresome

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

chromosomal region [inference]

chromosome, telomeric region

Displaying entries **1 - 5** of 10 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
damaged DNA binding	IDA	24939902
DNA binding	IDA	16762037
DNA-directed DNA polymerase activity	IBA IMP	16762037
metal ion binding	IEA
nucleotide binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity [inference]

DNA polymerase activity [inference]

DNA-directed DNA polymerase activity

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

nuclease activity [inference]

exonuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

3'-5'-DNA exonuclease activity

3'-5' exonuclease activity [inference]

3'-5'-DNA exonuclease activity

exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

3'-5'-DNA exonuclease activity

DNA nuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

3'-5'-DNA exonuclease activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA nuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

3'-5'-DNA exonuclease activity

DNA polymerase activity [inference]

DNA-directed DNA polymerase activity

binding [inference]

protein binding

enzyme binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

chromatin binding

metal cluster binding [inference]

iron-sulfur cluster binding [inference]

4 iron, 4 sulfur cluster binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

damaged DNA binding

nucleoside phosphate binding [inference]

nucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

polymerase

Functional Category

K: Transcription
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
4 iron, 4 sulfur cluster binding
iron-sulfur cluster binding
metal ion binding
nucleotide binding
nucleotidyltransferase activity
transferase activity

Displaying **all 10** entries
InterPro
C4-type zinc-finger of DNA polymerase delta
DNA polymerase family B, thumb domain
DNA polymerase, palm domain superfamily
DNA-directed DNA polymerase, family B, conserved site
DNA-directed DNA polymerase, family B, exonuclease domain
DNA-directed DNA polymerase, family B, multifunctional domain
DNA-directed DNA polymerase, family B
DNA/RNA polymerase superfamily
Ribonuclease H superfamily
Ribonuclease H-like superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:9256	colorectal cancer	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 65 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	18971		MGI:97741	MOUSE52371
Drosophila melanogaster	39746		FB:FBgn0263600
Rattus norvegicus	59294		RGD:621839	RATNO16010
Caenorhabditis elegans	179652		WB:WBGene00008645
Bos taurus	281990			BOVIN11592
Xenopus laevis	447518		Xenbase:XB-GENE-1002136
Pan troglodytes	456228	9598_0:004d42		PANTR19024
Pan troglodytes	469098			PANTR19024
Danio rerio	556456		ZFIN:ZDB-GENE-060429-1	DANRE30876
Xenopus tropicalis	734063		Xenbase:XB-GENE-1002131

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements