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MIRAGE
UDP glucuronosyltransferase family 1 member A1
Summary
- Gene Symbol
-
- UGT1A1
- Aliases
-
- UGT1A
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Cytoplasm
- Disease variant
- Endoplasmic reticulum
- Glycoprotein
- Glycosyltransferase
- Lipid metabolism
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of fatty acid metabolic process | ||
| xenobiotic metabolic process | ||
| negative regulation of cellular glucuronidation | ||
| flavonoid glucuronidation | ||
| negative regulation of glucuronosyltransferase activity |
|
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum | ||
| plasma membrane | ||
| cytochrome complex | ||
| endoplasmic reticulum chaperone complex | ||
| endoplasmic reticulum membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein heterodimerization activity | ||
| glucuronosyltransferase activity | ||
| enzyme inhibitor activity | ||
| protein binding | ||
| retinoic acid binding |
GO Hierarchy
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10211 | cholelithiasis | |
| DOID:11151 | cholecystolithiasis | |
| DOID:1380 | endometrial cancer | |
| DOID:1612 | breast cancer | |
| DOID:2043 | hepatitis B | |
| DOID:2394 | ovarian cancer | |
| DOID:2739 | Gilbert syndrome | |
| DOID:2741 | bilirubin metabolic disorder | |
| DOID:3803 | Crigler-Najjar syndrome | |
| DOID:3908 | lung non-small cell carcinoma |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001392 | Abnormality of the liver |
| HP:0001399 | Hepatic failure |
| HP:0002354 | Memory impairment |
| HP:0002910 | Elevated circulating hepatic transaminase concentration |
| HP:0003265 | Neonatal hyperbilirubinemia |
| HP:0003577 | Congenital onset |
| HP:0003623 | Neonatal onset |
| HP:0006579 | Prolonged neonatal jaundice |
| HP:0008176 | Neonatal unconjugated hyperbilirubinemia |
| HP:0008282 | Unconjugated hyperbilirubinemia |
| Disease ID | Disease Name |
|---|---|
| OMIM:218800 |
|
| OMIM:143500 |
|
| OMIM:606785 |
|
| OMIM:237900 |
|
| ORPHA:79235 |
|
| ORPHA:79234 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
