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protein kinase cAMP-activated catalytic subunit beta

Summary

Gene Symbol

PRKACB

Organism

Homo sapiens (human)

External Links

NCBI Gene

5567

PubChem

5567

Alliance of Genome Resources

HGNC:9381

JoGo

PRKACB

TogoVar

PRKACB

Annotation

Keyword

ATP-binding
Alternative splicing
Cell membrane
Cytoplasm
Disease variant
Myristate
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Serine/threonine-protein kinase
cAMP

Proteins

Displaying **all 6** entries
UniProt	Protein Name
B1APF9
B7ZA00
B2RB89
A0A087WVC4
B1APG3
P22694

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
neural tube closure	IEA
renal water homeostasis	TAS
protein phosphorylation	IDA	12420224 21880142
signal transduction	IBA
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	TAS	12420224

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular process [inference]

signal transduction

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

protein kinase A signaling

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to fluid shear stress [inference]

cellular response to laminar fluid shear stress [inference]

vascular endothelial cell response to laminar fluid shear stress

vascular endothelial cell response to fluid shear stress [inference]

vascular endothelial cell response to laminar fluid shear stress

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly [inference]

high-density lipoprotein particle assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly [inference]

high-density lipoprotein particle assembly

protein-lipid complex organization [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly [inference]

high-density lipoprotein particle assembly

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle assembly [inference]

high-density lipoprotein particle assembly

multicellular organismal process [inference]

system process [inference]

renal system process [inference]

renal water homeostasis

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis [inference]

renal water homeostasis

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle assembly [inference]

high-density lipoprotein particle assembly

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

tube formation [inference]

tube closure [inference]

neural tube closure

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis [inference]

renal water homeostasis

chemical homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis [inference]

renal water homeostasis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to fluid shear stress [inference]

cellular response to laminar fluid shear stress [inference]

vascular endothelial cell response to laminar fluid shear stress

vascular endothelial cell response to fluid shear stress [inference]

vascular endothelial cell response to laminar fluid shear stress

response to fluid shear stress [inference]

response to laminar fluid shear stress [inference]

cellular response to laminar fluid shear stress [inference]

vascular endothelial cell response to laminar fluid shear stress

cellular response to fluid shear stress [inference]

cellular response to laminar fluid shear stress [inference]

vascular endothelial cell response to laminar fluid shear stress

vascular endothelial cell response to fluid shear stress [inference]

vascular endothelial cell response to laminar fluid shear stress

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to fluid shear stress [inference]

cellular response to laminar fluid shear stress [inference]

vascular endothelial cell response to laminar fluid shear stress

vascular endothelial cell response to fluid shear stress [inference]

vascular endothelial cell response to laminar fluid shear stress

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of protein maturation [inference]

regulation of protein processing

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of protein maturation [inference]

regulation of protein processing

regulation of nitrogen compound metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

regulation of protein processing

regulation of protein maturation [inference]

regulation of protein processing

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of protein maturation [inference]

regulation of protein processing

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

regulation of protein processing

regulation of protein maturation [inference]

regulation of protein processing

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

regulation of protein processing

regulation of protein maturation [inference]

regulation of protein processing

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

regulation of intracellular signal transduction [inference]

regulation of TOR signaling [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

regulation of TORC1 signaling [inference]

negative regulation of TORC1 signaling

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

regulation of intracellular signal transduction [inference]

regulation of TOR signaling [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

regulation of TORC1 signaling [inference]

negative regulation of TORC1 signaling

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

regulation of cellular process [inference]

signal transduction

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

protein kinase A signaling

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

regulation of intracellular signal transduction [inference]

regulation of TOR signaling [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

regulation of TORC1 signaling [inference]

negative regulation of TORC1 signaling

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of protein maturation [inference]

regulation of protein processing

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

regulation of biological quality [inference]

regulation of body fluid levels [inference]

multicellular organismal-level water homeostasis [inference]

renal water homeostasis

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
plasma membrane	IEA
cAMP-dependent protein kinase complex	TAS	12420224
cAMP-dependent protein kinase complex	IBA
extracellular exosome	HDA	23533145
ciliary base	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

cAMP-dependent protein kinase complex

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

protein kinase complex [inference]

serine/threonine protein kinase complex [inference]

cAMP-dependent protein kinase complex

cellular anatomical entity [inference]

nucleoplasm

microtubule organizing center [inference]

centrosome

cytosol

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

nucleus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

ciliary base

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
magnesium ion binding	IDA	12420224
protein serine/threonine kinase activity	TAS
AMP-activated protein kinase activity
cAMP-dependent protein kinase activity	TAS
cAMP-dependent protein kinase activity	IDA	12420224 31112131