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cAMP-dependent protein kinase catalytic subunit beta

Summary

UniProt ID

P22694

Gene Symbol

PRKACB

Organism

Homo sapiens (human)

External Links

GlyGen: P22694
PubChem: P22694
The Human Metabolome Database: HMDBP01415
The O-GlcNAc Database: P22694
RaftProt: P22694
O-GlcNAcAtlas: P22694

Annotation

Keyword

ATP-binding
Alternative splicing
Cell membrane
Cytoplasm
Disease variant
Myristate
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
cAMP

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
renal water homeostasis
protein phosphorylation
signal transduction
regulation of protein processing
negative regulation of smoothened signaling pathway
neural tube closure
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
protein kinase A signaling
high-density lipoprotein particle assembly
negative regulation of TORC1 signaling

Displaying **all 8** entries
GO Term
nucleus
plasma membrane
extracellular exosome
cytosol
nucleoplasm
centrosome
cAMP-dependent protein kinase complex
ciliary base

Displaying **all 7** entries
GO Term
ubiquitin protein ligase binding
magnesium ion binding
AMP-activated protein kinase activity
cAMP-dependent protein kinase activity
ATP binding
protein serine kinase activity
protein serine/threonine kinase activity

Annotation information from UniProt.

Sequence

MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
253			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 26 in total

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Pathway Name	Organism
ADORA2B mediated anti-inflammatory cytokines production	Homo sapiens
CD209 (DC-SIGN) signaling	Homo sapiens
CREB1 phosphorylation through the activation of Adenylate Cyclase	Homo sapiens
DARPP-32 events	Homo sapiens
Degradation of GLI1 by the proteasome	Homo sapiens
Degradation of GLI2 by the proteasome	Homo sapiens
FCGR3A-mediated IL10 synthesis	Homo sapiens
Factors involved in megakaryocyte development and platelet production	Homo sapiens
GLI3 is processed to GLI3R by the proteasome	Homo sapiens
GPER1 signaling	Homo sapiens