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tyrosyl-DNA phosphodiesterase 1
Summary
- Gene Symbol
-
- TDP1
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| single strand break repair | ||
| single strand break repair | ||
| DNA repair | ||
| DNA repair | ||
| double-strand break repair |
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| nucleoplasm | ||
| cytoplasm | ||
| plasma membrane | ||
| intracellular membrane-bounded organelle |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| double-stranded DNA binding | ||
| double-stranded DNA binding | ||
| single-stranded DNA binding | ||
| single-stranded DNA binding | ||
| exonuclease activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Tyrosyl-DNA phosphodiesterase
- Functional Category
-
- L: Replication, recombination and repair
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| 3'-tyrosyl-DNA phosphodiesterase activity |
| DNA repair |
| double-stranded DNA binding |
| hydrolase activity |
| nuclease activity |
| InterPro |
|---|
| Tyrosyl-DNA phosphodiesterase I |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0090115 | spinocerebellar ataxia with axonal neuropathy 1 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100153247 | PIGXX32977 | ||
| 100225761 | TAEGU25854 | ||
| 100349532 | RABIT08951 | ||
| 100388128 | CALJA02264 | ||
| 100432320 | PONAB08068 | ||
| 100550592 | MELGA11055 | ||
| 100563188 | ANOCA00103 | ||
| 100593301 | NOMLE22101 | ||
| 100662744 | LOXAF16153 | ||
| 100699881 | ORENI35662 |
