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tyrosyl-DNA phosphodiesterase 1
Summary
- Gene Symbol
-
- TDP1
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| single strand break repair | ||
| single strand break repair | ||
| DNA repair | ||
| DNA repair | ||
| double-strand break repair |
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| nucleoplasm | ||
| cytoplasm | ||
| plasma membrane | ||
| intracellular membrane-bounded organelle |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| double-stranded DNA binding | ||
| double-stranded DNA binding | ||
| single-stranded DNA binding | ||
| single-stranded DNA binding | ||
| exonuclease activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Tyrosyl-DNA phosphodiesterase
- Functional Category
-
- L: Replication, recombination and repair
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| 3'-tyrosyl-DNA phosphodiesterase activity |
| DNA repair |
| double-stranded DNA binding |
| hydrolase activity |
| nuclease activity |
| InterPro |
|---|
| Tyrosyl-DNA phosphodiesterase I |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0090115 | spinocerebellar ataxia with axonal neuropathy 1 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 102011360 | CHILA10583 | ||
| 102184066 | CAPHI00022 | ||
| 102295915 | HAPBU00914 | ||
| 102348571 | LATCH15896 | ||
| 102460027 | PELSI08915 | ||
| 102787593 | NEOBR00074 | ||
| 103136011 | POEFO04479 | ||
| 103257673 | CARSF19244 | ||
| 103379302 | CYNSE24402 | ||
| 103462197 | POERE23608 |
