mitogen-activated protein kinase kinase 6

Summary
Gene Symbol
  • MAP2K6
Organism
Homo sapiens (human)
NCBI Gene
5608
PubChem
5608
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Acetylation
  • Alternative splicing
  • Apoptosis
  • Cytoskeleton
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Serine/threonine-protein kinase
  • Stress response
  • Transcription regulation
  • Tyrosine-protein kinase
Proteins
Displaying all 2 entries
UniProt Protein Name
P52564
  • MAPK/ERK kinase 6
  • Stress-activated protein kinase kinase 3
A8K3Y2
Gene Ontology (GO)
Displaying entries 1 - 5 of 26 in total
GO Term Evidence Code PMID
MAPK cascade
MAPK cascade
osteoblast differentiation
response to ischemia
apoptotic process
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
kinase kinase
Functional Category
  • E: Amino acid transport and metabolism
  • Q: Secondary metabolites biosynthesis, transport and catabolism
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying all 5 entries
DO ID Disease Name Source
DOID:11870 Pick's disease
DOID:397 restrictive cardiomyopathy
DOID:4001 ovarian carcinoma
DOID:4362 cervical cancer
DOID:678 progressive supranuclear palsy

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025