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gasdermin C
Summary
- Gene Symbol
-
- GSDMC
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Cell membrane
- Cytoplasm
- Necrosis
- Palmitate
- Reference proteome
- Transmembrane beta strand
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9BYG8 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| programmed cell death | ||
| defense response to bacterium | ||
| transmembrane transport | ||
| pyroptosis | ||
| pyroptosis |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytoplasm | ||
| cytosol | ||
| plasma membrane | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| phosphatidylserine binding | ||
| phosphatidylinositol-4,5-bisphosphate binding | ||
| wide pore channel activity | ||
| phosphatidylinositol-4-phosphate binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- gasdermin-C-like
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| phosphatidylinositol-4,5-bisphosphate binding |
| phosphatidylinositol-4-phosphate binding |
| phosphatidylserine binding |
| pyroptosis |
| InterPro |
|---|
| Gasdermin, PUB domain |
| Gasdermin, pore forming domain |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 56169 | RGD:1308989 | ||
| 74548 | MOUSE15269 | ||
| 83492 | MOUSE15245 | ||
| 270328 | MOUSE15266 | ||
| 299908 | RATNO39291 | ||
| 331063 | MOUSE15260 | ||
| 508492 | BOVIN05729 | ||
| 695343 | MACMU44017 | ||
| 741746 | PANTR43258 | ||
| 100151870 | PIGXX22868 |
