GlyCosmos Portal

Submissions

SLAM family member 8

Summary

Gene Symbol

SLAMF8

Organism

Homo sapiens (human)

External Links

NCBI Gene

56833

PubChem

56833

Alliance of Genome Resources

HGNC:21391

Annotation

Keyword

Alternative splicing
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin domain
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9P0V8	B-lymphocyte activator macrophage expressed BCM-like membrane protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
leukocyte chemotaxis involved in inflammatory response	ISS
B-1 B cell lineage commitment	ISS	11313408
immune response	IBA
negative regulation of macrophage chemotaxis	ISS
regulation of NAD(P)H oxidase activity	ISS

GO Hierarchy

biological process

immune system process [inference]

immune response

leukocyte migration [inference]

leukocyte migration involved in inflammatory response [inference]

leukocyte chemotaxis involved in inflammatory response

leukocyte chemotaxis [inference]

leukocyte chemotaxis involved in inflammatory response

cellular process [inference]

cellular developmental process [inference]

cell fate commitment [inference]

B cell lineage commitment [inference]

B-1 B cell lineage commitment

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte migration involved in inflammatory response [inference]

leukocyte chemotaxis involved in inflammatory response

leukocyte chemotaxis [inference]

leukocyte chemotaxis involved in inflammatory response

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

leukocyte chemotaxis involved in inflammatory response

developmental process [inference]

cellular developmental process [inference]

cell fate commitment [inference]

B cell lineage commitment [inference]

B-1 B cell lineage commitment

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

leukocyte chemotaxis involved in inflammatory response

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH reduction [inference]

phagosome acidification

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH reduction [inference]

phagosome acidification

monoatomic cation homeostasis [inference]

regulation of pH [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH reduction [inference]

phagosome acidification

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH reduction [inference]

phagosome acidification

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH reduction [inference]

phagosome acidification

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium

immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

biological regulation [inference]

regulation of pH [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH reduction [inference]

phagosome acidification

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of neutrophil migration

negative regulation of macrophage migration [inference]

negative regulation of macrophage chemotaxis

negative regulation of immune effector process [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of neutrophil migration

negative regulation of macrophage migration [inference]

negative regulation of macrophage chemotaxis

regulation of leukocyte chemotaxis [inference]

negative regulation of leukocyte chemotaxis [inference]

regulation of macrophage chemotaxis [inference]

negative regulation of macrophage chemotaxis

regulation of monocyte chemotaxis [inference]

negative regulation of monocyte chemotaxis

regulation of dendritic cell chemotaxis [inference]

negative regulation of dendritic cell chemotaxis

regulation of mononuclear cell migration [inference]

negative regulation of mononuclear cell migration [inference]

regulation of monocyte chemotaxis [inference]

negative regulation of monocyte chemotaxis

regulation of dendritic cell chemotaxis [inference]

negative regulation of dendritic cell chemotaxis

regulation of neutrophil migration [inference]

negative regulation of neutrophil migration

regulation of macrophage migration [inference]

regulation of macrophage chemotaxis [inference]

negative regulation of macrophage chemotaxis

negative regulation of macrophage migration [inference]

negative regulation of macrophage chemotaxis

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of B cell differentiation

regulation of B cell activation [inference]

regulation of B cell differentiation

regulation of immune effector process [inference]

negative regulation of immune effector process [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of immune response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of B cell differentiation

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of respiratory burst [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of cellular metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of kinase activity

regulation of respiratory burst [inference]

regulation of respiratory burst involved in inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of respiratory burst [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of chemotaxis [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of neutrophil migration

negative regulation of macrophage migration [inference]

negative regulation of macrophage chemotaxis

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

negative regulation of leukocyte chemotaxis [inference]

regulation of macrophage chemotaxis [inference]

negative regulation of macrophage chemotaxis

regulation of monocyte chemotaxis [inference]

negative regulation of monocyte chemotaxis

regulation of dendritic cell chemotaxis [inference]

negative regulation of dendritic cell chemotaxis

negative regulation of chemotaxis [inference]

negative regulation of leukocyte chemotaxis [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of neutrophil migration

negative regulation of macrophage migration [inference]

negative regulation of macrophage chemotaxis

regulation of leukocyte chemotaxis [inference]

negative regulation of leukocyte chemotaxis [inference]

regulation of macrophage chemotaxis [inference]

negative regulation of macrophage chemotaxis

regulation of monocyte chemotaxis [inference]

negative regulation of monocyte chemotaxis

regulation of dendritic cell chemotaxis [inference]

negative regulation of dendritic cell chemotaxis

regulation of mononuclear cell migration [inference]

negative regulation of mononuclear cell migration [inference]

regulation of monocyte chemotaxis [inference]

negative regulation of monocyte chemotaxis

regulation of dendritic cell chemotaxis [inference]

negative regulation of dendritic cell chemotaxis

regulation of neutrophil migration [inference]

negative regulation of neutrophil migration

regulation of macrophage migration [inference]

regulation of macrophage chemotaxis [inference]

negative regulation of macrophage chemotaxis

negative regulation of macrophage migration [inference]

negative regulation of macrophage chemotaxis

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of neutrophil migration

negative regulation of macrophage migration [inference]

negative regulation of macrophage chemotaxis

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of neutrophil migration

negative regulation of macrophage migration [inference]

negative regulation of macrophage chemotaxis

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of neutrophil migration

negative regulation of macrophage migration [inference]

negative regulation of macrophage chemotaxis

negative regulation of immune effector process [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of metabolic process [inference]

negative regulation of respiratory burst [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of locomotion [inference]

negative regulation of chemotaxis [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of neutrophil migration

negative regulation of macrophage migration [inference]

negative regulation of macrophage chemotaxis

negative regulation of cellular process [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of neutrophil migration

negative regulation of macrophage migration [inference]

negative regulation of macrophage chemotaxis

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of chemotaxis [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of multicellular organismal process [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of innate immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of chemotaxis [inference]

negative regulation of leukocyte chemotaxis [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

negative regulation of leukocyte chemotaxis [inference]

regulation of macrophage chemotaxis [inference]

negative regulation of macrophage chemotaxis

regulation of monocyte chemotaxis [inference]

negative regulation of monocyte chemotaxis

regulation of dendritic cell chemotaxis [inference]

negative regulation of dendritic cell chemotaxis

negative regulation of chemotaxis [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of chemotaxis [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of immune response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

negative regulation of inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of innate immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of cell development [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of B cell differentiation

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of B cell differentiation

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of kinase activity

regulation of cell differentiation [inference]

regulation of cell development [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of B cell differentiation

negative regulation of cellular process [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of neutrophil migration

negative regulation of macrophage migration [inference]

negative regulation of macrophage chemotaxis

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of B cell differentiation

regulation of B cell activation [inference]

regulation of B cell differentiation

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of neutrophil migration

negative regulation of macrophage migration [inference]

negative regulation of macrophage chemotaxis

regulation of leukocyte chemotaxis [inference]

negative regulation of leukocyte chemotaxis [inference]

regulation of macrophage chemotaxis [inference]

negative regulation of macrophage chemotaxis

regulation of monocyte chemotaxis [inference]

negative regulation of monocyte chemotaxis

regulation of dendritic cell chemotaxis [inference]

negative regulation of dendritic cell chemotaxis

regulation of mononuclear cell migration [inference]

negative regulation of mononuclear cell migration [inference]

regulation of monocyte chemotaxis [inference]

negative regulation of monocyte chemotaxis

regulation of dendritic cell chemotaxis [inference]

negative regulation of dendritic cell chemotaxis

regulation of neutrophil migration [inference]

negative regulation of neutrophil migration

regulation of macrophage migration [inference]

regulation of macrophage chemotaxis [inference]

negative regulation of macrophage chemotaxis

negative regulation of macrophage migration [inference]

negative regulation of macrophage chemotaxis

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of neutrophil migration

negative regulation of macrophage migration [inference]

negative regulation of macrophage chemotaxis

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of leukocyte migration [inference]

negative regulation of leukocyte chemotaxis [inference]

negative regulation of mononuclear cell migration [inference]

negative regulation of neutrophil migration

negative regulation of macrophage migration [inference]

negative regulation of macrophage chemotaxis

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of B cell differentiation

regulation of B cell activation [inference]

regulation of B cell differentiation

negative regulation of multicellular organismal process [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of respiratory burst involved in inflammatory response [inference]

negative regulation of respiratory burst involved in inflammatory response

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of B cell differentiation

regulation of biological quality [inference]

regulation of intracellular pH [inference]

intracellular pH reduction [inference]

phagosome acidification

regulation of molecular function [inference]

regulation of catalytic activity [inference]

regulation of transferase activity [inference]

regulation of kinase activity

regulation of oxidoreductase activity [inference]

regulation of NAD(P)H oxidase activity

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cell surface	NAS	11313408
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32296183 33961781
signaling receptor activity	ISS
signaling receptor activity	IBA
identical protein binding	ISS

GO Hierarchy

molecular function

binding [inference]

protein binding

identical protein binding

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

SLAM family member 6

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Ortholog

Displaying entries **31 - 34** of 34 in total

« First

‹ Prev

1

2

3

4
Species	Gene ID	Orthologous MAtrix
Gorilla gorilla gorilla	109025058	GORGO44889
Phascolarctos cinereus	110201882	PHACI13923
Vombatus ursinus	114026354	VOMUR28245
Ornithorhynchus anatinus	114807923	ORNAN32282

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements