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Rho GTPase activating protein 21

Summary

Gene Symbol

ARHGAP21

Organism

Homo sapiens (human)

External Links

NCBI Gene

57584

PubChem

57584

Alliance of Genome Resources

HGNC:23725

Annotation

Keyword

3D-structure
Alternative splicing
Cell junction
Cytoplasmic vesicle
Cytoskeleton
GTPase activation
Golgi apparatus
Isopeptide bond
Membrane
Methylation
Phosphoprotein
Reference proteome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5T5U3	Rho GTPase-activating protein 10 Rho-type GTPase-activating protein 21

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
Golgi organization	IMP	20525016
signal transduction	IEA
regulation of small GTPase mediated signal transduction	TAS
Golgi localization	IBA
establishment of Golgi localization	IDA	20525016

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

transport along microtubule [inference]

organelle transport along microtubule

signal transduction

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

organelle transport along microtubule

maintenance of location in cell [inference]

maintenance of organelle location [inference]

maintenance of Golgi location

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

Golgi organization

localization [inference]

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

organelle transport along microtubule

microtubule-based transport [inference]

transport along microtubule [inference]

organelle transport along microtubule

establishment of localization in cell [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

organelle transport along microtubule

establishment of Golgi localization

establishment of organelle localization [inference]

maintenance of location [inference]

maintenance of location in cell [inference]

maintenance of organelle location [inference]

maintenance of Golgi location

organelle localization [inference]

Golgi localization

establishment of organelle localization [inference]

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

organelle transport along microtubule

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of cellular process [inference]

signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
Golgi membrane	IEA
Golgi apparatus	IDA	20525016
cytosol	TAS
plasma membrane	IDA
actin cytoskeleton	IDA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane

bounding membrane of organelle [inference]

Golgi membrane

cell junction

anchoring junction

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

Displaying **all 2** entries
GO Term	Evidence Code	PMID
GTPase activator activity	TAS
protein binding	IPI	15161933 15778465 17347647 20195357 28514442 33961781 36931259

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Rho gtpase-activating protein

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Rho GTPase activation protein
Rho GTPase-activating protein domain

Ortholog

Displaying entries **1 - 10** of 65 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	57584	Xenbase:XB-GENE-1011028
Drosophila melanogaster	58996	FB:FBgn0031118
Mus musculus	71435	Xenbase:XB-GENE-1011028	MOUSE32998
Rattus norvegicus	307178		RATNO12922
Pan troglodytes	450355		PANTR00319
Macaca mulatta	706428		MACMU45721
Monodelphis domestica	100025310		MONDO35168
Ornithorhynchus anatinus	100074543		ORNAN04541
Taeniopygia guttata	100231539		TAEGU18703
Callithrix jacchus	100390028		CALJA41613