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BRCA1 associated RING domain 1

Summary

Gene Symbol

BARD1

Organism

Homo sapiens (human)

External Links

NCBI Gene

580

PubChem

580

Alliance of Genome Resources

HGNC:952

Annotation

Keyword

3D-structure
ANK repeat
Alternative splicing
DNA repair
Isopeptide bond
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Transferase
Ubl conjugation
Ubl conjugation pathway
Zinc-finger

Proteins

Displaying **all 7** entries
UniProt	Protein Name
F6MDI2
F6MDI0
A0A087WZ19
F6MDI1
A0AVN2
Q99728	RING-type E3 ubiquitin transferase BARD1
C9IYG1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
tissue homeostasis	TAS	15782130
DNA repair	NAS	22369660
regulation of DNA repair	NAS	20656689
chromatin remodeling	TAS	35351360
regulation of transcription by RNA polymerase II	TAS	35351360

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA recombination [inference]

homologous recombination

DNA strand resection involved in replication fork processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K6-linked ubiquitination

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA recombination [inference]

homologous recombination

DNA strand resection involved in replication fork processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA recombination [inference]

homologous recombination

DNA strand resection involved in replication fork processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA recombination [inference]

homologous recombination

DNA strand resection involved in replication fork processing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA recombination [inference]

homologous recombination

DNA strand resection involved in replication fork processing

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K6-linked ubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K6-linked ubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K6-linked ubiquitination

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA recombination [inference]

homologous recombination

DNA strand resection involved in replication fork processing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA recombination [inference]

homologous recombination

DNA strand resection involved in replication fork processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination [inference]

protein K6-linked ubiquitination

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic G2/M transition checkpoint

cell cycle process [inference]

mitotic cell cycle process [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic G2/M transition checkpoint

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA recombination [inference]

homologous recombination

DNA strand resection involved in replication fork processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA recombination [inference]

homologous recombination

DNA strand resection involved in replication fork processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA recombination [inference]

homologous recombination

DNA strand resection involved in replication fork processing

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein location in nucleus [inference]

negative regulation of protein export from nucleus

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

DNA repair

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

DNA repair

response to abiotic stimulus [inference]

response to radiation [inference]

response to ionizing radiation [inference]

cellular response to ionizing radiation

cellular response to radiation [inference]

cellular response to ionizing radiation

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

DNA repair

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation

localization [inference]

maintenance of location [inference]

maintenance of protein location [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein location in nucleus [inference]

negative regulation of protein export from nucleus

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein location in nucleus [inference]

negative regulation of protein export from nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of DNA metabolic process [inference]

regulation of DNA repair

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA 3'-end processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of DNA metabolic process [inference]

regulation of DNA repair

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA 3'-end processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of DNA metabolic process [inference]

regulation of DNA repair

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA 3'-end processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of DNA metabolic process [inference]

regulation of DNA repair

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA 3'-end processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of cell cycle checkpoint [inference]

regulation of DNA damage checkpoint

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of nucleocytoplasmic transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

negative regulation of transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of nucleocytoplasmic transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of protein localization [inference]

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cell cycle

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic G2/M transition checkpoint

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic G2/M transition checkpoint

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

negative regulation of protein localization [inference]

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of cell cycle checkpoint [inference]

regulation of DNA damage checkpoint

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic G2/M transition checkpoint

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of cell cycle checkpoint [inference]

regulation of DNA damage checkpoint

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of DNA metabolic process [inference]

regulation of DNA repair

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of mRNA metabolic process [inference]

regulation of mRNA processing [inference]

regulation of mRNA 3'-end processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA 3'-end processing

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cell cycle

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic G2/M transition checkpoint

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic G2/M transition checkpoint

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

negative regulation of protein localization [inference]

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of cell cycle

regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic G2/M transition checkpoint

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

regulation of cell cycle process [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic G2/M transition checkpoint

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

regulation of cell cycle phase transition [inference]

regulation of cell cycle checkpoint [inference]

regulation of DNA damage checkpoint

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic G2/M transition checkpoint

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

regulation of cell cycle G2/M phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

negative regulation of cell cycle

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic G2/M transition checkpoint

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

negative regulation of cell cycle G2/M phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic G2/M transition checkpoint

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G2/M transition of mitotic cell cycle [inference]

mitotic G2/M transition checkpoint

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of nucleocytoplasmic transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of protein export from nucleus

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

negative regulation of protein export from nucleus

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

negative regulation of protein localization [inference]

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein export from nucleus

regulation of cellular response to stress [inference]

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GO Term	Evidence Code	PMID
ubiquitin ligase complex	NAS	14976165
nuclear ubiquitin ligase complex	IDA	14636569
nucleus	NAS	18171670 20656689 22369660
nucleus	IDA	14636569 15265711 9342365
nucleus	IMP	15632137

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

nuclear ubiquitin ligase complex

BRCA1-BARD1 complex

intracellular protein-containing complex [inference]

ubiquitin ligase complex

nuclear ubiquitin ligase complex

BRCA1-BARD1 complex

catalytic complex [inference]

transferase complex [inference]

ubiquitin ligase complex

nuclear ubiquitin ligase complex

BRCA1-BARD1 complex

cellular anatomical entity [inference]

nuclear body [inference]

nuclear speck

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

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GO Term	Evidence Code	PMID
RNA binding	IDA	12419249
ubiquitin-protein transferase activity	NAS	15905410
ubiquitin-protein transferase activity	IDA	12890688 20351172
ubiquitin-protein transferase activity	IBA
protein binding	IPI	10026184 10477523 15184379 15265711 15383276 15782130 17873885 19117993 19369211 20351172 20379136 22110403 23680151 24981860 25416956 29656893 31270457 31515488 32296183 33961781 34591612 8944023

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity

ubiquitin protein ligase activity [inference]

histone ubiquitin ligase activity [inference]

histone H2A ubiquitin ligase activity [inference]

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity [inference]

histone ubiquitin ligase activity [inference]

histone H2A ubiquitin ligase activity [inference]

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity

ubiquitin protein ligase activity [inference]

histone ubiquitin ligase activity [inference]

histone H2A ubiquitin ligase activity [inference]

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity [inference]

histone ubiquitin ligase activity [inference]

histone H2A ubiquitin ligase activity [inference]

histone modifying activity [inference]

histone ubiquitin ligase activity [inference]

histone H2A ubiquitin ligase activity [inference]

binding [inference]

protein binding

enzyme binding [inference]

kinase binding

histone binding [inference]

ubiquitin modification-dependent histone binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

modification-dependent protein binding [inference]

ubiquitination-like modification-dependent protein binding [inference]

ubiquitin-dependent protein binding [inference]

ubiquitin modification-dependent histone binding

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

brca1-associated ring domain protein 1

Functional Category

K: Transcription
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
BRCT domain superfamily
BRCT domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:1612	breast cancer	Alliance of Genome Resources
DOID:2394	ovarian cancer	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	580	Xenbase:XB-GENE-492035
Mus musculus	12021	Xenbase:XB-GENE-492035	MOUSE30115
Rattus norvegicus	64557		RATNO43727
Pan troglodytes	470638		PANTR29705
Bos taurus	530961		BOVIN24705
Canis lupus familiaris	610190		CANLF14196
Macaca mulatta	694301		MACMU05660
Monodelphis domestica	100014337		MONDO32318
Equus caballus	100053962		HORSE37554
Ornithorhynchus anatinus	100090768		ORNAN24416

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements