GlyCosmos Portal

Submissions

butyrylcholinesterase

Summary

Gene Symbol

BCHE

Organism

Homo sapiens (human)

External Links

NCBI Gene

590

PubChem

590

Alliance of Genome Resources

HGNC:983

Annotation

Keyword

3D-structure
Direct protein sequencing
Disease variant
Disulfide bond
Phosphoprotein
Reference proteome
Secreted
Serine esterase
Sialic acid
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P06276	Acylcholine acylhydrolase Butyrylcholine esterase Choline esterase II Pseudocholinesterase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
choline metabolic process	IBA
xenobiotic metabolic process	TAS
response to folic acid	IEA
peptide hormone processing	TAS
negative regulation of synaptic transmission	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing

ammonium ion metabolic process [inference]

choline metabolic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing

acetylcholine metabolic process [inference]

acetylcholine catabolic process

alkaloid metabolic process [inference]

tropane alkaloid metabolic process [inference]

cocaine metabolic process

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing

protein maturation [inference]

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing

choline metabolic process

organonitrogen compound catabolic process [inference]

acetylcholine catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

organonitrogen compound catabolic process [inference]

acetylcholine catabolic process

hormone metabolic process [inference]

peptide hormone processing

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

cocaine metabolic process

xenobiotic metabolic process

heterocycle metabolic process [inference]

tropane alkaloid metabolic process [inference]

cocaine metabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing

protein maturation [inference]

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing

protein maturation [inference]

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing

acetate ester metabolic process [inference]

acetylcholine metabolic process [inference]

acetylcholine catabolic process

organic cyclic compound metabolic process [inference]

tropane alkaloid metabolic process [inference]

cocaine metabolic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing

acetylcholine metabolic process [inference]

acetylcholine catabolic process

alkaloid metabolic process [inference]

tropane alkaloid metabolic process [inference]

cocaine metabolic process

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing

protein maturation [inference]

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing

choline metabolic process

organonitrogen compound catabolic process [inference]

acetylcholine catabolic process

organic substance catabolic process [inference]

organonitrogen compound catabolic process [inference]

acetylcholine catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

cocaine metabolic process

xenobiotic metabolic process

heterocycle metabolic process [inference]

tropane alkaloid metabolic process [inference]

cocaine metabolic process

cellular developmental process [inference]

cell differentiation [inference]

neuroblast differentiation

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning

behavior [inference]

learning or memory [inference]

learning

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

neuroblast differentiation

response to stimulus [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to nutrient [inference]

response to vitamin [inference]

response to folic acid

response to endogenous stimulus [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to chemical [inference]

response to nutrient [inference]

response to vitamin [inference]

response to folic acid

response to organic substance [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to organonitrogen compound [inference]

response to organic cyclic compound [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to folic acid

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to oxygen-containing compound [inference]

response to folic acid

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

negative regulation of synaptic transmission

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell communication [inference]

negative regulation of synaptic transmission

regulation of cellular process [inference]

regulation of cell communication [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

negative regulation of synaptic transmission

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell communication [inference]

negative regulation of synaptic transmission

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

peptide hormone processing

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
blood microparticle	HDA	22516433
plasma membrane	IBA
extracellular space	IBA
extracellular region	NAS TAS	14718574
nuclear envelope lumen	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle envelope lumen [inference]

nuclear envelope lumen

blood microparticle

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
choline binding	IEA
amyloid-beta binding	NAS	11569538
cholinesterase activity	IDA	19452557
catalytic activity	NAS	11569538
protein binding	IPI	28514442 32296183 32814053 33961781

GO Hierarchy

molecular function

catalytic activity

hydrolase activity [inference]

hydrolase activity, acting on ester bonds

carboxylic ester hydrolase activity [inference]

cholinesterase activity

acetylcholinesterase activity

binding [inference]

protein binding

amide binding [inference]

peptide binding [inference]

amyloid-beta binding

ion binding [inference]

cation binding [inference]

choline binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying entries **1 - 10** of 21 in total

1

2

3

Next ›

Last »
DO ID	Disease Name	Source
DOID:0050784	primary progressive multiple sclerosis	Alliance of Genome Resources
DOID:10113	trypanosomiasis	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:10914	amnestic disorder	Alliance of Genome Resources
DOID:1168	familial hyperlipidemia	Alliance of Genome Resources
DOID:12858	Huntington's disease	Alliance of Genome Resources
DOID:1307	dementia	Alliance of Genome Resources
DOID:1826	epilepsy	Alliance of Genome Resources
DOID:2297	leptospirosis	Alliance of Genome Resources