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MIRAGE
Cholinesterase

Summary
UniProt ID
P06276
Gene Symbol
  • BCHE
  • CHE1
Gene ID
590
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011403
GlyConnect
GlyGen
P06276
PubChem
P06276
The Human Metabolome Database
HMDBP00525
Re-Glyco
P06276
Annotation
Keyword
  • 3D-structure
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Phosphoprotein
  • Reference proteome
  • Secreted
  • Serine esterase
  • Sialic acid
  • Signal
Gene Ontology (GO)
Displaying all 6 entries
GO Term
extracellular region
extracellular space
plasma membrane
endoplasmic reticulum lumen
nuclear envelope lumen
blood microparticle
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MHSKVTIICIRFLFWFLLLCMLIGKSHTEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKVLEMTGNIDEAEWEWKAGFHRWNNYMMDWKNQFNDYTSKKESCVGL
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying entries 1 - 10 of 12 in total
Position Description PubMed ID GlyTouCan ID Source
45 N-linked (GlcNAc...) (complex) asparagine
85 N-linked (GlcNAc...) (complex) asparagine
134 N-linked (GlcNAc...) (complex) asparagine
256
269 N-linked (GlcNAc...) (complex) asparagine
284 N-linked (GlcNAc...) (complex) asparagine
369 N-linked (GlcNAc...) (complex) asparagine
483 N-linked (GlcNAc...) (complex) asparagine
507
509 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 4 entries
Pathway Name Organism
Aspirin ADME Homo sapiens
Neurotransmitter clearance Homo sapiens
Synthesis of PC Homo sapiens
Synthesis, secretion, and deacylation of Ghrelin Homo sapiens
Disease
Displaying all 7 entries
DO ID Disease Name Source
DOID:10652 Alzheimer's disease
DOID:1826 epilepsy
DOID:3393 coronary artery disease
DOID:4247 coronary restenosis
DOID:655 inherited metabolic disorder
DOID:9352 type 2 diabetes mellitus
DOID:9744 type 1 diabetes mellitus
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025