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selectin L

Summary

Gene Symbol

SELL

Aliases

CD62L
LAM-1
LAM1
LSEL
Leu-8
Lyam-1
PLNHR
hLHRc

Organism

Homo sapiens (human)

External Links

NCBI Gene

6402

HGNC

10720

KEGG Gene ID

hsa:6402

PubChem

6402

Alliance of Genome Resources

HGNC:10720

Annotation

Keyword

3D-structure
Alternative initiation
Calcium
Cell adhesion
Cell membrane
Disulfide bond
EGF-like domain
Glycoprotein
Lectin
Metal-binding
Reference proteome
Repeat
Signal
Sushi
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P14151	CD62 antigen-like family member L Leukocyte adhesion molecule 1 Leukocyte surface antigen Leu-8 Leukocyte-endothelial cell adhesion molecule 1 Lymph node homing receptor TQ1 gp90-MEL

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IBA
response to cytokine	IBA
leukocyte cell-cell adhesion		32887674
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IMP	28011641
leukocyte tethering or rolling	IBA IMP	28011641

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell-cell adhesion [inference]

leukocyte cell-cell adhesion

leukocyte adhesion to vascular endothelial cell [inference]

leukocyte tethering or rolling

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine

Displaying **all 4** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IBA
plasma membrane	IDA TAS	2663882 28011641
extracellular space	IBA
secretory granule membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane

bounding membrane of organelle [inference]

secretory granule membrane

side of membrane [inference]

external side of plasma membrane

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GO Term	Evidence Code	PMID
oligosaccharide binding	IBA IMP	28011641
heparin binding		7680663
glycosphingolipid binding		7680663
calcium ion binding	IDA	28011641
sialic acid binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

protease binding

lipid binding [inference]

sphingolipid binding [inference]

glycosphingolipid binding

glycolipid binding [inference]

glycosphingolipid binding

carbohydrate binding

oligosaccharide binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

sialic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

sialic acid binding

cation binding [inference]

metal ion binding [inference]

calcium ion binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sialic acid binding

glycolipid binding [inference]

glycosphingolipid binding

sulfur compound binding [inference]

heparin binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000188404

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K06495

Name

selectin, lymphocyte

References

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:9415	allergic asthma	DisGeNET
DOID:9452	steatotic liver disease	DisGeNET
DOID:9534	tuberculous pneumothorax	DisGeNET
DOID:9538	multiple myeloma	DisGeNET
DOID:9744	type 1 diabetes mellitus	DisGeNET Alliance of Genome Resources
DOID:999	hypereosinophilic syndrome	DisGeNET DisGeNET

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	32447	FB:FBgn0030617
Xenopus laevis	108713555	Xenbase:XB-GENE-17345286
Ornithorhynchus anatinus	103170504		ORNAN07468
Sarcophilus harrisii	100921084		SARHA06103
Erinaceus europaeus	103121282		ERIEU13997
Callithrix jacchus	100413273		CALJA16765
Cercocebus atys	105600162		CERAT38045
Macaca fascicularis	102142895		MACFA19730
Macaca mulatta	701419		MACMU24140
Macaca nemestrina	105493032		MACNE35728

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements