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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
matrix metallopeptidase 25
Summary
- Gene Symbol
-
- MMP25
- Aliases
-
- MT6-MMP
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Calcium
- Cell membrane
- Cleavage on pair of basic residues
- Disulfide bond
- Extracellular matrix
- GPI-anchor
- Metal-binding
- Metalloprotease
- Reference proteome
- Repeat
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9NPA2 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis |
|
|
| inflammatory response |
|
|
| extracellular matrix organization | ||
| collagen catabolic process | ||
| hard palate development |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular matrix |
|
|
| plasma membrane | ||
| extracellular space | ||
| side of membrane | ||
| membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metalloendopeptidase activity | ||
| zinc ion binding | ||
| protein binding |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110052 | amelogenesis imperfecta type 1B | |
| DOID:0110053 | amelogenesis imperfecta type 4 | |
| DOID:0110054 | amelogenesis imperfecta type 1A | |
| DOID:0110055 | amelogenesis imperfecta type 3A | |
| DOID:0110056 | amelogenesis imperfecta type 1C | |
| DOID:0110057 | amelogenesis imperfecta type 2A1 | |
| DOID:0110058 | amelogenesis imperfecta type 1E | |
| DOID:0110059 | X-linked amelogenesis imperfecta hypoplastic/hypomaturation 2 | |
| DOID:0110060 | amelogenesis imperfecta hypomaturation type 2A2 | |
| DOID:0110061 | amelogenesis imperfecta hypomaturation type 2A3 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 186805 | WB:WBGene00010423 | ||
| 35997 | FB:FBgn0033438 | ||
| 100001739 | ZFIN:ZDB-GENE-070820-22 | ||
| 100333601 | ZFIN:ZDB-GENE-100308-4 | ||
| 103030877 | ASTMX04478 | ||
| 100306863 | SALSA92376 | ||
| 115156327 | SALTR00746 | ||
| 115531195 | GADMO22093 | ||
| 100706082 | ORENI71216 | ||
| 115571563 | SPAAU32264 |
