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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Matrix metalloproteinase-25
Summary
- UniProt ID
- Q9NPA2
- Gene Symbol
-
- MMP25
- MMP20
- MMPL1
- MT6MMP
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q9NPA2
- PubChem
- Q9NPA2
- The Human Metabolome Database
- HMDBP07810
Annotation
- Keyword
-
- Calcium
- Cell membrane
- Cleavage on pair of basic residues
- Disulfide bond
- Extracellular matrix
- GPI-anchor
- Metal-binding
- Metalloprotease
- Reference proteome
- Repeat
- Signal
- Zinc
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| proteolysis |
| inflammatory response |
| extracellular matrix organization |
| collagen catabolic process |
| hard palate development |
| GO Term |
|---|
| extracellular space |
| plasma membrane |
| membrane |
| extracellular matrix |
| side of membrane |
| specific granule membrane |
| GO Term |
|---|
| metalloendopeptidase activity |
| zinc ion binding |
Sequence
MRLRLRLLALLLLLLAPPARAPKPSAQDVSLGVDWLTRYGYLPPPHPAQAQLQSPEKLRDAIKVMQRFAGLPETGRMDPGTVATMRKPRCSLPDVLGVAGLVRRRRRYALSGSVWKKRTLTWRVRSFPQSSQLSQETVRVLMSYALMAWGMESGLTFHEVDSPQGQEPDILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFGSKDGEGTDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLYGKAPQTPYDKPTRKPLAPPPQPPASPTHSPSFPIPDRCEGNFDAIANIRGETFFFKGPWFWRLQPSGQLVSPRPARLHRFWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQDRQLEGGARPLTELGLPPGEEVDAVFSWPQNGKTYLVRGRQYWRYDEAAARPDPGYPRDLSLWEGAPPSPDDVTVSNAGDTYFFKGAHYWRFPKNSIKTEPDAPQPMGPNWLDCPAPSSGPRAPRPPKATPVSETCDCQCELNQAAGRWPAPIPLLLLPLLVGGVASR
Glycosylation Sites
G43417UB
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of Matrix Metalloproteinases | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110052 | amelogenesis imperfecta type 1B | |
| DOID:0110053 | amelogenesis imperfecta type 4 | |
| DOID:0110054 | amelogenesis imperfecta type 1A | |
| DOID:0110055 | amelogenesis imperfecta type 3A | |
| DOID:0110056 | amelogenesis imperfecta type 1C | |
| DOID:0110057 | amelogenesis imperfecta type 2A1 | |
| DOID:0110058 | amelogenesis imperfecta type 1E | |
| DOID:0110059 | X-linked amelogenesis imperfecta hypoplastic/hypomaturation 2 | |
| DOID:0110060 | amelogenesis imperfecta hypomaturation type 2A2 | |
| DOID:0110061 | amelogenesis imperfecta hypomaturation type 2A3 |
