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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
C-type lectin domain containing 7A
Summary
- Gene Symbol
-
- CLEC7A
- Aliases
-
- CD369
- DECTIN-1
- SCARE2
- hDectin-1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Cytoplasm
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Innate immunity
- Lectin
- Metal-binding
- Phosphoprotein
- Proteomics identification
- Receptor
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A0S2Z5Q1 |
|
| Q9BXN2 |
|
| Q68D78 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of cell maturation | ||
| positive regulation of superoxide anion generation | ||
| cellular response to molecule of fungal origin | ||
| positive regulation of monocyte chemotactic protein-1 production | ||
| positive regulation of cytokine production involved in inflammatory response |
GO Hierarchy
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of respiratory burst
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of respiratory burst
- positive regulation of cell population proliferation
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of cell population proliferation
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of nitric oxide biosynthetic process
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-2 production
- positive regulation of interleukin-23 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of cytokine production involved in inflammatory response
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of protein metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of response to stimulus [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| (1->3)-beta-D-glucan binding | ||
| MHC protein binding |
|
|
| pattern recognition receptor activity | ||
| metal ion binding | ||
| carbohydrate binding |
GO Hierarchy
KEGG BRITE Database
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0040085 | bacterial sepsis | |
| DOID:0050133 | superficial mycosis | |
| DOID:0050167 | autoimmune polyendocrine syndrome type 1 | |
| DOID:0050486 | exanthem | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050734 | congenital intrinsic factor deficiency | |
| DOID:0060041 | autism spectrum disorder | |
| DOID:0060180 | colitis | |
| DOID:0060189 | ileitis | |
| DOID:0060190 | ileocolitis |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000010 | Recurrent urinary tract infections |
| HP:0000142 | Abnormal vagina morphology |
| HP:0000153 | Abnormality of the mouth |
| HP:0000159 | Abnormal lip morphology |
| HP:0000478 | Abnormality of the eye |
| HP:0000504 | Abnormality of vision |
| HP:0000682 | Abnormal dental enamel morphology |
| HP:0000790 | Hematuria |
| HP:0000951 | Abnormality of the skin |
| Disease ID | Disease Name |
|---|---|
| ORPHA:1334 |
|
| OMIM:613108 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 178506 | WB:WBGene00009156 | ||
| 103168706 | ORNAN09203 | ||
| 100400667 | CALJA44428 | ||
| 105587994 | CERAT39972 | ||
| 102115991 | MACFA02516 | ||
| 105499923 | MACNE16801 | ||
| 101009125 | PAPAN39926 | ||
| 105542003 | MANLE19787 | ||
| 101152217 | GORGO06045 | ||
| 100994924 | PANPA08699 |
