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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
C-type lectin domain family 7 member A
Summary
- UniProt ID
- Q9BXN2
- Gene Symbol
-
- CLEC7A
- BGR
- CLECSF12
- DECTIN1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q9BXN2
- PubChem
- Q9BXN2
- The Human Metabolome Database
- HMDBP12648
- The O-GlcNAc Database
- Q9BXN2
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Cytoplasm
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Innate immunity
- Lectin
- Metal-binding
- Phosphoprotein
- Receptor
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| plasma membrane |
| membrane |
| cell surface |
| GO Term |
|---|
| pattern recognition receptor activity |
| metal ion binding |
| carbohydrate binding |
| MHC protein binding |
| identical protein binding |
| (1->3)-beta-D-glucan binding |
Sequence
MEYHPDLENLDEDGYTQLHFDSQSNTRIAVVSEKGSCAASPPWRLIAVILGILCLVILVIAVVLGTMAIWRSNSGSNTLENGYFLSRNKENHSQPTQSSLEDSVTPTKAVKTTGVLSSPCPPNWIIYEKSCYLFSMSLNSWDGSKRQCWQLGSNLLKIDSSNELGFIVKQVSSQPDNSFWIGLSRPQTEVPWLWEDGSTFSSNLFQIRTTATQENPSPNCVWIHVSVIYDQLCSVPSYSICEKKFSM
Glycosylation Sites
G53434XO
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CLEC7A (Dectin-1) signaling | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:869 | cholesteatoma | |
| DOID:0040085 | bacterial sepsis | |
| DOID:12663 | blastomycosis | |
| DOID:0050133 | superficial mycosis | |
| DOID:0050167 | autoimmune polyendocrine syndrome type 1 | |
| DOID:0050486 | exanthem | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050734 | congenital intrinsic factor deficiency | |
| DOID:0060041 | autism spectrum disorder | |
| DOID:0060180 | colitis |
